D. Scadden

Molecular Biology · 2000–2019

A researcher in the Science corpus: 26 papers; trusts 9 researchers and is trusted by 46 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 186 citations into it; #981 of 17,773 by trust here, #581 by citations
• Hematology — 122 citations into it; #128 of 225 by trust here, #9 by citations
• Genetics — 97 citations into it; #858 of 6,854 by trust here, #153 by citations
• Oncology — 74 citations into it; #119 of 1,698 by trust here, #195 by citations
• Immunology — 73 citations into it
• Cell Biology — 30 citations into it
• Cellular and Molecular Neuroscience — 10 citations into it
• Plant Science — 6 citations into it

Whom D. Scadden trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. T. Xie
2. A. Spradling
3. B. Ohlstein
4. S. Shi
5. T. Palmer
6. Keisuke Ito
7. S. Morrison
8. Linheng Li
9. Qin Shen

Who trusts D. Scadden overall

1. A. Pocheville
2. F. Gattazzo
3. Richard J. Gilbertson
4. B. Psaila
5. N. Sims
6. Hu Zhang
7. Valentine Svensson
8. G. T. Huang
9. N. Frank
10. Ahmed Mohyeldin

Papers from D. Scadden's perspective

Ordered by how strongly the researchers D. Scadden trusts endorse each paper. Same corpus, a different order for every researcher.

1. A niche maintaining germ line stem cells in the Drosophila ovary. (Science)
2. Stem cells find their niche (Nature)
3. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells (Nature)
4. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. (Science)
5. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells (Nature)
6. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
7. The relationship between the spleen colony-forming cell and the haemopoietic stem cell.
8. Stem cells, cancer, and cancer stem cells (Nature)
9. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells (Nature)
10. Endothelial Cells Stimulate Self-Renewal and Expand Neurogenesis of Neural Stem Cells (Science)

Their papers

• Bayesian approach to single-cell differential expression analysis (2014) — 1,271 citations
• Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer (2004) — 2,071 citations
• AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. (2007) — 1,814 citations
• Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (2006) — 1,103 citations
• Hematopoietic stem cell quiescence maintained by p21cip1/waf1. (2000) — 1,390 citations
• Osteoblastic cells regulate the haematopoietic stem cell niche (2003) — 3,638 citations
• The stem-cell niche as an entity of action (2006) — 1,944 citations
• Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation (2008) — 915 citations
• Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells (2000) — 1,693 citations
• Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. (2005) — 597 citations
• In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment (2005) — 909 citations
• Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration (2012) — 618 citations
• Bone progenitor dysfunction induces myelodysplasia and secondary leukemia (2010) — 1,105 citations
• BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. (2013) — 760 citations
• Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood. (2005) — 692 citations
• A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia (2019) — 741 citations
• Distinct bone marrow blood vessels differentially regulate hematopoiesis (2016) — 643 citations
• The bone marrow niche for haematopoietic stem cells (2014) — 2,259 citations
• Direct measurement of local oxygen concentration in the bone marrow of live animals (2014) — 1,069 citations
• Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis (2012) — 836 citations