Osteoblastic cells regulate the haematopoietic stem cell niche

By L. Calvi, G. Adams, K. Weibrecht, J. Weber, D. P. Olson, M. Knight, Roderick P. Martin, E. Schipani, P. Divieti, F. Bringhurst and 3 more. Nature, 2003

3,638 citations recorded by the source corpus.

Subfields: Genetics, Hematology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6f3cba94795a526a6bcce8679fa0216c441bd354

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. S. Morrison
2. P. Robey
3. Linheng Li
4. G. Semenza
5. P. Bianco
6. A. Trumpp
7. Anne Wilson
8. Stuart H. Orkin

In Hematology

1. S. Morrison
2. G. Semenza
3. A. Trumpp
4. P. Frenette
5. Anne Wilson
6. Linheng Li
7. T. Suda
8. Leonard I. Zon

In Molecular Biology

1. S. Morrison
2. Linheng Li
3. M. Clarke
4. A. Spradling
5. A. Trumpp
6. D. Scadden
7. Anne Wilson
8. Irving L. Weissman

Citations in the corpus

• The placenta is a niche for hematopoietic stem cells. (2004, background): “…marrow supports both self-renewal and differentiation of HSCs in specialized microenvironmental niches (Arai et al., 2004; Avecilla et al., 2004; Calvi et al., 2003; Nilsson et al., 2001; Tokoyoda et al., 2004; Zhang et al., 2003a), whereas embryonic hematopoiesis is compartmentalized into…”
• Stem cells and cancer: two faces of eve. (2006, background): “Recent studies suggest that cellular niches are important in preventing mammalian stem cell expansion (Calvi et al., 2003; Zhang et al., 2003).”
• Metabolic regulation of hematopoietic stem cells in the hypoxic niche. (2011, background): “Adaptation of HSCs to a Hypoxic Microenvironment Several studies have suggested that LT-HSCs reside primarily in the endosteal zone of the BM (Calvi et al., 2003; Zhang et al., 2003; Arai et al., 2004).”
• Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. (2007, background): “The multipotency of at least a subset of CFU-Fs supports the view that a second type of stem cell (skeletal [Bianco and Robey, 2004], stromal [Owen and Friedenstein, 1988], or ‘‘mesenchymal’’ [Caplan, 1991]) coexists with HSCs in BM. Due to the lack of markers suited to bridge the gap between in sit”