A niche maintaining germ line stem cells in the Drosophila ovary.
By T. Xie, A. Spradling. Science, 2000
829 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/0b865cba0586dbeaa998445f40daf70ed16a7681
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In Cellular and Molecular Neuroscience
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Citations in the corpus
- Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks (2011, background): “During normal development and tissue homeostasis, these extrinsic factors are provided by cellular and extracellular elements that define the stem cell niche (24, 25).”
- Asymmetric and symmetric stem-cell divisions in development and cancer (2006, background): “A classic example of an asymmetric division that is controlled by an extrinsic mechanism is provided by the Drosophila germline stem cell, which divides with a reproducible orientation to generate one daughter that remains in the stem-cell niche and retains stem-cell identity, and one daughter tha”
- Normal stem cells and cancer stem cells: the niche matters. (2006, background): “For example, genetic ablation of the germ line stem cell niche in flies results in loss of stem cells (54).”
- Stem cells find their niche (2001, background): “Nonetheless, the presence of a niche has been shown directly by a different approac”
- Identification of the haematopoietic stem cell niche and control of the niche size (2003, background): “The stem cell niche has been described in the Drosophila ovar”
- The Hedgehog and Wnt signalling pathways in cancer (2001, background): “Stem-cell number and growth rate are maintained by multiple signals received from the microenvironment or nich”
- Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. (2008, background): “The stem cell supplying the replacement may lie nearby (Xie and Spradling, 2000; Jin et al., 2008), or a daughter cell may migrate over a distance, suggesting that it can actively home to an appropriate niche (Nystul and Spradling, 2007).”
- Stem cells, ageing and the quest for immortality (2006, background): “Studies of the importance of such changes in the stem-cell niche have been best described in the germline stem-cell niche in Drosophila”
- SCARECROW is involved in positioning the stem cell niche in the Arabidopsis root meristem. (2003, background): “Cap cells (Xie and Spradling 1998, 2000) and somatic hub cells (Kiger et al. 2001; Tulina and Matunis 2001) in Drosophila, distal tip cells in Caenorhabditis elegans (Kimble and White 1981), and cells expressing the homeodomain transcription factor WUSCHEL in the Arabidopsis shoot apical meristem…”
- Bone-marrow haematopoietic-stem-cell niches (2006, background): “melanogaster ovarian and testicular niches controlling germline stem-cell maintenance and differentiation were the first to be characterize”
- Mechanisms of asymmetric stem cell division. (2008, background): “Upon GSC loss, the remaining GSCs can divide parallel to the cap cells and thereby generate two daughter cells, which maintain niche contact and stem cell identity (Xie and Spradling, 2000).”
- Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size (2005, background): “In organisms such as Drosophila, for example, it is well defined that contact of stem cells with hub cells in the germarium are required for the preservation of stem cells (2).”
- 1.3 – Vitellogenesis and Post-Vitellogenic Maturation of the Insect Ovarian Follicle (2005, background): “, hedgehog (hh), piwi, fs(1)Yb, and decapentapalegic (dpp), whose function is required for the maintenance of stem cell function (Cox et al., 1998; Xie and Spradling, 1998; King and Lin, 1999; Cox et al., 2000; Xie and Spradling, 2000; King et al., 2001) (see Chapter 1.”