In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment

By D. Sipkins, Xunbin Wei, Juwell W. Wu, J. Runnels, D. Côté, T. Means, A. Luster, D. Scadden, Charles P Lin. Nature, 2005

909 citations recorded by the source corpus.

Subfields: Immunology and Allergy, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/3442498bbb2a2dd5ae0a46a63213138e512b865c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology and Allergy

1. Vasilis Ntziachristos
2. Erik Sahai

In Molecular Biology

1. Richard J. Gilbertson
2. Vasilis Ntziachristos
3. H. Kronenberg
4. Erik Sahai
5. Leonard I. Zon
6. Stuart H. Orkin
7. D. Scadden
8. P. Dirks

In Oncology

1. Richard J. Gilbertson
2. Vasilis Ntziachristos
3. Erik Sahai
4. D. Scadden
5. P. Dirks

Citations in the corpus

• The stem-cell niche as an entity of action (2006, background): “The sites on such vessels where primitive cells engage and diapedese seem to be highly discontinuous, and are functionally distinguished by abundant CXCL12 and E-selectin expressio”
• A perivascular niche for brain tumor stem cells. (2007, background): “, 2005), and that bone marrow endothelial niches are required for the homing and retention of normal hematopoietic and leukemic stem cells (Kiel et al., 2005; Sipkins et al., 2005).”
• Arteriolar niches maintain haematopoietic stem cell quiescence (2013, neutral): “…may represent a proliferative niche is consistent with recent studies indicating that E-selectin, an adhesion molecule constitutively expressed in certain BM sinusoid microdomains 43 , promotes HSC proliferation and blockade of E-selectin protects HSCs following chemotherapy or γ -irradiation 44 .”
• Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration (2012, methodology): “Fourteen days after 4-OHT treatment, we scanned both sides of the sagittal (S.S.) and coronal (C.S.) sutures, which permitted examination of 40%–60% of the calvarial cavities of the mouse (Sipkins et al., 2005) (Figure 1B, left panel).”
• Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2 mediated regeneration of sinusoidal endothelial cells (2009, neutral): “SECs have a unique expression of adhesion molecules, allowing the trafficking and homing of HSPCs to the BM (Kataoka and Tavassoli, 1985; Naiyer et al., 1999; Rafii et al., 1994, 1995; Sipkins et al., 2005; Kollet et al., 2006; Slayton et al., 2007).”
• Hematopoiesis: an evolving paradigm for stem cell biology. (2008, methodology): “As assessed by intravital microscopy, HSCs appear to reside in the periosteal region of calverium marrow (Sipkins et al., 2005).”
• Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging (2006, neutral): “dtd" [ ]> Although optical absorption is strongly associated with the physiological status of biological tissue, existing high-resolution optical imaging modalities, including confocal microscop”
• BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. (2013, neutral): “Using in vivo confocal imaging, we were able to visualize the BM vasculature and the possible presence of GFP + MM cells (38).”