Polyunsaturated fatty acid metabolism in Atlantic salmon (Salmo salar) undergoing parr-smolt transformation and the effects of dietary linseed and rapeseed oils

By D. Tocher, J. Bell, J. Dick, R. Henderson, F. McGhee, D. Michell, P. C. Morris. Fish Physiology & Biochemistry, 2000

201 citations recorded by the source corpus.

Subfields: Aquatic Science, Immunology, Nature and Landscape Conservation

View Paper: https://www.semanticscholar.org/paper/6dd37ce0b5c4a21c58dfbae38fec485c88aafe2d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Aquatic Science

1. D. Tocher
2. J. Bell
3. G. Turchini
4. Wing Ng
5. Ester Santigosa
6. Marie Vagner
7. B. Torstensen
8. J. Dick

In Immunology

1. D. Tocher
2. J. Bell
3. Wing Ng
4. G. Turchini
5. Ester Santigosa
6. Marie Vagner
7. J. Dick
8. G. Mourente

In Nature and Landscape Conservation

1. J. Bell
2. Wing Ng
3. B. Torstensen
4. G. Turchini

Citations in the corpus

• Molecular Cloning and Functional Characterization of Fatty Acyl Desaturase and Elongase cDNAs Involved in the Production of Eicosapentaenoic and Docosahexaenoic Acids from α-Linolenic Acid in Atlantic Salmon (Salmo salar) (2004, background): “…linseed oil containing high levels of 18:3n-3, the increased activity of the desaturation/elongation pathway cannot convert 18:3n-3 to EPA and DHA efficiently enough to prevent the accumulation of 18:3n-3 and depletion of EPA and DHA in the tissues (Bell et al., 1997; Tocher et al., 2000, 2001).”
• Arachidonic acid in aquaculture feeds: current status and future opportunities (2003, background): “Fish fed diets containing a 1:1 (w/w) ratio of rapeseed oil and linseed oil, or rapeseed oil alone, had increased ARA and ARA/EPA ratio in their gill phospholipids (PL), compared to fish fed fish oil (Bell et al., 1997a; Tocher et al., 2000).”
• Effects of diets containing linseed oil on fatty acid desaturation and oxidation in hepatocytes and intestinal enterocytes in Atlantic salmon (Salmo salar) (2002, methodology): “The methodology for preparing hepatocytes as above was specifically developed for use in the field and has been successfully used in several previous trials (Bell et al. 1997, 2001a, 2002a; Tocher et al. 1997, 2000, 2001).”
• Characterization and modulation of gene expression and enzymatic activity of delta-6 desaturase in teleosts: A review (2011, background): “Moreover, replacing FOs by VOs consistently resulted in increased Δ6D activity in freshwater fish (Bell et al., 1997, 2001, 2002; Tocher et al., 1997, 2000, 2001a,b, 2002, 2003a,b, 2004, 2006b; Zheng et al., 2005a,b); this was also seen in mammals (Brenner, 1981a,b).”
• Rapeseed oil as an alternative to marine fish oil in diets of post-smolt Atlantic salmon (Salmo salar): changes in flesh fatty acid composition and effectiveness of subsequent fish oil “wash out” (2003, background): “Several studies have confirmed that salmon can grow normally on diets containing high levels of vegetable oils and that they are able to convert 18:3n-3 and 18:2n-6 to their longer chain, highly unsaturated fatty acid (HUFA) products, including 20:5n-3, 22:6n-3 and 20:4n-6 (Bell et al., 1997; Tocher”
• Effects of dietary lipid level and vegetable oil on fatty acid metabolism in Atlantic salmon (Salmo salar L.) over the whole production cycle (2003, methodology): “…earlier trials (Bell et al. 1997) and supports our hypothesis that the peak in activity coincides with the completion of the parr-smolt transformation and that variation in its temporal relationship to seawater transfer is because transfer is an artificially imposed time point (Tocher et al. 2000).”
• Effect of partial substitution of dietary fish oil by vegetable oils on desaturation and β-oxidation of [1-14C]18:3n−3 (LNA) and [1-14C]20:5n−3 (EPA) in hepatocytes and enterocytes of European sea bass (Dicentrarchus labrax L.) (2005, background): “Numerous studies have shown that inclusion of vegetable oils in diets for freshwater and diadromous fish species increases hepatic fatty acid desaturase activities (Buzzi et al., 1996; Bell et al., 1997; Tocher et al., 1997, 2000, 2001a,b).”
• Fish oil replacement in finfish nutrition (2009, background): “(1995) reported no sensorial differences in the fillets of brook charr fed either FO, C ⁄RO or SBO, whereas Torstensen et al. (2005) reported several organoleptic differences in the flesh of Atlantic salmon fed FO or a blended VO.”
• Nutritional regulation of hepatocyte fatty acid desaturation and polyunsaturated fatty acid composition in zebrafish (Danio rerio) and tilapia (Oreochromis niloticus) (2001, background): “…that the hepatic desaturation of 18:3n-3 and 18:2n-6 was significantly greater in Atlantic salmon fed diets containing vegetable oils rich in 18:2n-6 and 18:3n-3 compared to fish fed diets containing fish oils rich in the long-chain HUFA, EPA and DHA (Bell et al. 1997; Tocher et al. 1997, 2000).”
• Parr–smolt transformation and dietary vegetable lipids affect intestinal nutrient uptake, barrier function and plasma cortisol levels in Atlantic salmon (2007, unknown): “This includes an increase in fatty acid elongase and desaturase activity of isolated hepatocytes as well as increases in the ratio of C20 and C22:C18 and n-3:n-6 fatty acids in salmonid tissue (Tocher et al., 2000, 2004).”
• Safe and Nutritious Aquaculture Produce: Benefits and Risks of Alternative Sustainable Aquafeeds (2008, background): “2001) or LO (Bell et al. 1997, 2003a; Tocher et al. 2000) as full, or partial, replacement of FO and suggest that the energy requirements of salmon can be satisfied by VO with variable fatty acid compositions.”