Nutritional regulation of hepatocyte fatty acid desaturation and polyunsaturated fatty acid composition in zebrafish (Danio rerio) and tilapia (Oreochromis niloticus)

By D. Tocher, M. Agaba, N. Hastings, J. Bell, J. Dick, A. Teale. Fish Physiology & Biochemistry, 2001

155 citations recorded by the source corpus.

Subfields: Aquatic Science, Immunology, Physiology

View Paper: https://www.semanticscholar.org/paper/b2fd2f9dad88cd859f20b811729652bc8812092c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Aquatic Science

1. D. Tocher
2. Ester Santigosa
3. Marie Vagner
4. J. Bell
5. G. Mourente
6. J. Dick
7. Xiaozhong Zheng
8. C. Lawrence

In Immunology

1. D. Tocher
2. Ester Santigosa
3. Marie Vagner
4. J. Bell
5. G. Mourente
6. J. Dick
7. Xiaozhong Zheng
8. Wing Ng

In Physiology

1. D. Tocher
2. Ester Santigosa
3. Marie Vagner
4. C. Lawrence
5. J. Bell
6. G. Mourente
7. J. Dick
8. Carl Smith

Citations in the corpus

• Effect of partial substitution of dietary fish oil by vegetable oils on desaturation and β-oxidation of [1-14C]18:3n−3 (LNA) and [1-14C]20:5n−3 (EPA) in hepatocytes and enterocytes of European sea bass (Dicentrarchus labrax L.) (2005, background): “…radioactivity from [1-14C]18:3n-3 in products of Δ6 desaturation and C18-20 elongation (18:4n-3 and 20:4n-3, respectively) was generally greater than the recovery of radioactivity in Δ5 desaturated products, irrespective of dietary oil (Bell et al., 2001a,b, 2002; Tocher et al., 2001, 2002b, 2003).”
• The husbandry of zebrafish (Danio rerio): A review (2007, background): “…fatty acids (PUFAs) linoleate (18:2n-6) and linolenate (18:3n-3) into the physiologically more important highly unsaturated fatty acids (HUFAs), most notably eicosapentaenoic acid (20:5n-3; EPA), docsahexaenoic acid (22:6n-3; DHA), and arachidonic acid (20:4n-6; AA) (Tocher et al., 2001).”
• Characterization and modulation of gene expression and enzymatic activity of delta-6 desaturase in teleosts: A review (2011, background): “…conversion to 20:5n−3 [EPA] and 22:6n−3 [DHA] (Ruyter et al., 2000; Torstensen et al., 2000; Tortensen et al., 2005; Bell et al., 2001, 2002, 2003a,b; Tocher et al., 2001a,b, 2002, 2003a,b; Mourente and Dick, 2002; Seiliez et al., 2003; Zheng et al., 2005a,b; Francis et al., 2007, 2009; Vagner…”
• Effects of diets containing vegetable oil on expression of genes involved in highly unsaturated fatty acid biosynthesis in liver of Atlantic salmon (Salmo salar) (2004, background): “Increased gene expression could, at least in part, account for the higher activity of the HUFA biosynthesis pathway observed previously in fish fed vegetable oils compared to fish fed fish oil (Bell et al., 1997, 2001, 2002; Tocher et al., 1997, 2000, 2001a,b, 2002).”
• The behaviour and ecology of the zebrafish, Danio rerio (2007, background): “With the exception of their requirement for polyunsaturated fatty acids (Meinelt et al., 1999, 2000; Tocher et al., 2001) the nutritional demands of zebrafish are also unknown.”