R. Kastelein

Immunology · 2000–2012

A researcher in the Science corpus: 22 papers; trusts 6 researchers and is trusted by 35 researchers here, as inferred from the citation graph.

Subfields

• Immunology — 144 citations into it; #93 of 2,160 by trust here, #23 by citations
• Pathology and Forensic Medicine — 31 citations into it; #59 of 414 by trust here, #14 by citations

Whom R. Kastelein trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. G. Trinchieri
2. E. Bettelli

Who trusts R. Kastelein overall

1. E. Bettelli
2. T. Korn
3. C. Weaver
4. Y. Iwakura
5. Christopher A. Hunter
6. Wenjun Ouyang
7. A. Di Cesare
8. Jinfang Zhu

Papers from R. Kastelein's perspective

Ordered by how strongly the researchers R. Kastelein trusts endorse each paper. Same corpus, a different order for every researcher.

1. Microbial Lipopeptides Induce the Production of IL-17 in Th Cells1 (Journal of Immunology)
2. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
3. A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R1
4. Toll Pathway-Dependent Blockade of CD4+CD25+ T Cell-Mediated Suppression by Dendritic Cells (Science)
5. Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense (Journal of Experimental Medicine)
6. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells (Nature)
7. A novel transcription factor, T-bet, directs Th1 lineage commitment. (Cell)
8. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. (Proceedings of the National Academy of Sciences of the United States of America)
9. Interleukin-17 family members and inflammation. (Immunity)
10. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. (Immunity)

Their papers

• IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells (2012) — 1,058 citations
• IL‐23 and the Th17 pathway promote inflammation and impair antifungal immune resistance (2007) — 609 citations
• Development, cytokine profile and function of human interleukin 17–producing helper T cells (2007) — 2,200 citations
• Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. (2007) — 825 citations
• Understanding the IL-23-IL-17 immune pathway. (2006) — 823 citations
• IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. (2006) — 1,659 citations
• IL-23 promotes tumour incidence and growth (2006) — 1,013 citations
• Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. (2006) — 626 citations
• IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2–dependent mechanisms with implications for psoriasis pathogenesis (2006) — 708 citations
• IL-23 drives a pathogenic T cell population that induces autoimmune inflammation (2005) — 4,408 citations
• IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. (2005) — 3,782 citations
• Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. (2004) — 1,040 citations
• WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27 (2004) — 760 citations
• IL‐12 and IL‐23: master regulators of innate and adaptive immunity (2004) — 818 citations
• Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain (2003) — 3,127 citations
• Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation (2003) — 1,857 citations
• The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. (2003) — 1,001 citations
• A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R1 (2002) — 1,403 citations
• Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP (2002) — 2,211 citations
• IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. (2002) — 1,563 citations