Microbial Lipopeptides Induce the Production of IL-17 in Th Cells1

By C. Infante-Duarte, H. Horton, M. Byrne, T. Kamradt. Journal of Immunology, 2000

653 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/28d31910b82db77676a65f9bbe5e5f63f1308bf2

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In Immunology

Citations in the corpus

Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. (2005, background): “IL-17 is a proinflammatory cytokine expressed and secreted by T lymphocytes (Fossiez et al., 1996; Spriggs, 1997; Infante-Duarte et al., 2000; Yao et al., 1995b; Happel et al., 2003) that can induce G-CSF-dependent neutrophilia when expressed in mice (Schwarzenberger et al.”
Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense (2001, background): “Moreover, microbial lipopeptides have been shown to be potent inducers of IL-17 in T cells (23).”
The IL-17 family of cytokines in health and disease (2019, background): “IL-17 remained obscure throughout the 1990’s and early 2000’s, several early studies hinted that this cytokine was elevated in human inflammatory or autoimmune diseases and was expressed in a non-canonical T helper cell population (Albanesi et al., 1999; Antonysamy et al., 1999; Infante-Duarte et al”
Innate immunity in the central nervous system. (2012, neutral): “For example, IL-1 β can induce expression of TNF-α and IL-6, while IL-18 stimulates production of IL-17.”
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation (2005, background): “IL-17–producing T cells have also been identified in the synovial fluid of patients with Lyme arthritis (33), suggesting involvement of IL-17 in infection-induced immunopathology.”
IL‐12 and IL‐23: master regulators of innate and adaptive immunity (2004, background): “synovial fluid of patients with Lyme arthritis (82), suggesting”
IL-17, Produced by Lymphocytes and Neutrophils, Is Necessary for Lipopolysaccharide-Induced Airway Neutrophilia: IL-15 as a Possible Trigger (2003, background): “M urine IL-17, previously termed CTLA8, is a recently cloned cytokine (1) secreted by activated CD4 cells (2).”
IL-17-Mediated Regulation of Innate and Acquired Immune Response against Pulmonary Mycobacterium bovis Bacille Calmette-Guérin Infection1 (2007, result): “This finding is consistent with a report showing that exogenously added IL-17 affected neither Th1/Th2 phenotype differentiation nor IL-17 production (62).”