Alan Aderem

Immunology · 2000–2016

A researcher in the Science corpus: 19 papers; trusts 3 researchers and is trusted by 15 researchers here, as inferred from the citation graph.

Subfields

• Immunology — 89 citations into it; #302 of 2,160 by trust here, #97 by citations
• Molecular Biology — 73 citations into it; #9,431 of 17,773 by trust here, #2,599 by citations

Whom Alan Aderem trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. B. Cookson
2. R. Medzhitov
3. S. Fink

Who trusts Alan Aderem overall

1. P. Boksa
2. Shizuo Akira
3. A. Servin
4. D. Underhill
5. Klaas A. E. van't Slot
6. S. Iwanaga
7. Y. Wu
8. P. Matzinger
9. T. Horng
10. D. Klinman

Papers from Alan Aderem's perspective

Ordered by how strongly the researchers Alan Aderem trusts endorse each paper. Same corpus, a different order for every researcher.

1. Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells (Infection and Immunity)
2. Cryopyrin activates the inflammasome in response to toxins and ATP (Nature)
3. Caspase‐1‐dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages (Cellular Microbiology)
4. Salmonella induces macrophage death by caspase‐1‐dependent necrosis (Molecular Microbiology)
5. Pro-inflammatory programmed cell death. (Trends in Microbiology)
6. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 (Nature)
7. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation (Cell Death and Differentiation)
8. Salmonella interactions with host cells: type III secretion at work. (Annual Review of Cell and Developmental Biology)
9. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin (Nature Genetics)
10. Toll-like receptors. (Critical Care Medicine)

Their papers

• Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria (2010) — 1,280 citations
• Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf (2006) — 1,207 citations
• Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome (2010) — 812 citations
• Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans (2008) — 1,139 citations
• Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron (2004) — 1,812 citations
• Caspase-1 induced pyroptotic cell death (2011) — 1,085 citations
• Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity (2013) — 910 citations
• A prospective blood RNA signature for tuberculosis disease risk (2016) — 609 citations
• Systems Biology of Seasonal Influenza Vaccination in Humans (2011) — 724 citations
• Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4 (2006) — 770 citations
• Evasion of Toll-like receptor 5 by flagellated bacteria. (2005) — 692 citations
• The evolution of vertebrate Toll-like receptors. (2005) — 1,189 citations
• Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility (2003) — 863 citations
• A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease (2003) — 663 citations
• Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency (2003) — 674 citations
• The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 (2001) — 3,715 citations
• Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism (2001) — 768 citations
• The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. (2000) — 2,317 citations
• Toll-like receptors in the induction of the innate immune response (2000) — 3,279 citations