Pro-inflammatory programmed cell death.

By B. Cookson, Molly A. Brennan. Trends in Microbiology, 2001

1,196 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/83022baced2f3ab9e12714a6d37aec227d072a77

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Citations in the corpus

Pyroptotic cell death defends against intracellular pathogens (2015, background): “‘Pyro’, meaning fire, reflects the inflammatory nature of this form of cell death, and ‘ptosis’, meaning falling, matches the terms used for other forms of programmed cell death (2).”
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death. (2017, background): “To distinguish this proinflammatory ‘apoptosis’ from canonical apoptosis, Brad Cookson and his coworkers invented a new term, ‘pyroptosis’, in which the Greek roots ‘pyro’ and ‘ptosis’ mean heat/fever and falling off, respectively [74].”
Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. (2020, background): “Historically, pyroptosis refers to bacteria-induced, caspase-1-mediated monocyte death (Cookson and Brennan, 2001).”
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications. (2022, neutral): “Regulated, nonapoptotic cell death was then identified in the form of inflammatory cell death, termed pyroptosis (Cookson and Brennan, 2001), and necroptosis, a type of regulated necrosis (Degterev et al.”
From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways (2021, background): “These differences led to the introduction of the term pyroptosis [58,59].”
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018, background): “The term pyroptosis was originally coined by Cookson and Brennan to define a particular type of RCD partially resembling apoptosis but dependent on inflammatory CASP1 (and hence linked to pyrexia) [603], and several names including pyronecrosis have been introduced since to define partially related ”
Caspase-1 induced pyroptotic cell death (2011, background): “Pyroptosis was subsequently shown to be distinct from apoptosis (28, 29), and the name was coined in 2001 (30).”
Caspase‐1‐dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages (2006, background): “Caspase-1 has been implicated in non-infectious inflammatory diseases (Cookson and Brennan, 2001), suggesting that the caspase-1-mediated events occurring during pyroptosis may have broad biological significance.”