Johan Auwerx

Molecular Biology · 2000–2017

A researcher in the Science corpus: 30 papers; trusts 34 researchers and is trusted by 15 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 399 citations into it; #7,464 of 17,773 by trust here, #1,222 by citations
• Physiology — 336 citations into it; #184 of 2,276 by trust here, #27 by citations
• Geriatrics and Gerontology — 271 citations into it; #15 of 114 by trust here, #4 by citations
• Aging — 133 citations into it
• Oncology — 114 citations into it; #378 of 1,698 by trust here, #174 by citations
• Epidemiology — 103 citations into it; #2,045 of 2,148 by trust here, #737 by citations
• Surgery — 90 citations into it; #511 of 1,106 by trust here, #88 by citations
• Endocrine and Autonomic Systems — 37 citations into it

Whom Johan Auwerx trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. C. Cantó
2. R. Houtkooper
3. J. T. Rodgers
4. M. Haigis
5. L. Guarente
6. P. Puigserver
7. B. Rogina
8. S. Imai
9. H. Tissenbaum
10. Su-Ju Lin

Who trusts Johan Auwerx overall

1. C. Cantó
2. J. Y. Chiang
3. E. Verdin
4. R. Houtkooper
5. Jun Yoshino

Papers from Johan Auwerx's perspective

Ordered by how strongly the researchers Johan Auwerx trusts endorse each paper. Same corpus, a different order for every researcher.

1. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. (Science)
2. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans (Nature)
3. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration (Nature)
4. Calorie restriction extends yeast life span by lowering the level of NADH. (Genes & Development)
5. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ (Nature)
6. Increased Nuclear NAD Biosynthesis and SIRT1 Activation Prevent Axonal Degeneration (Science)
7. Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase (Science)
8. Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. (Molecules and Cells)
9. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. (Nature)
10. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae (Nature)

Their papers

• Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity (2004) — 1,741 citations
• AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity (2009) — 3,126 citations
• Mitonuclear protein imbalance as a conserved longevity mechanism (2013) — 994 citations
• Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle (2010) — 919 citations
• Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. (2004) — 1,321 citations
• Mitonuclear communication in homeostasis and stress (2016) — 699 citations
• Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis. (2011) — 1,184 citations
• Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome (2003) — 872 citations
• Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. (2000) — 1,500 citations
• Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents (2016) — 930 citations
• Nuclear receptors and the control of metabolism. (2003) — 662 citations
• International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors (2006) — 1,003 citations
• Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals (2017) — 751 citations
• NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice (2016) — 1,152 citations
• NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus (2015) — 1,456 citations
• The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling (2013) — 1,146 citations
• Sirtuins as regulators of metabolism and healthspan (2012) — 1,942 citations
• The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet induced obesity (2012) — 1,193 citations
• Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ (2012) — 972 citations
• PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation (2011) — 812 citations