Luke A. O'Neill
Immunology · 2000–2018
A researcher in the Science corpus: 36 papers; trusts 36 researchers and is trusted by 43 researchers here, as inferred from the citation graph.
Subfields
- Immunology — 497 citations into it; #71 of 2,160 by trust here, #67 by citations
- Molecular Biology — 303 citations into it; #7,194 of 17,773 by trust here, #2,699 by citations
- Cancer Research — 264 citations into it; #572 of 1,780 by trust here, #287 by citations
- Epidemiology — 91 citations into it; #803 of 2,148 by trust here, #925 by citations
- Oncology — 61 citations into it; #1,443 of 1,698 by trust here, #912 by citations
- Physiology — 50 citations into it
- Infectious Diseases — 20 citations into it
- Biochemistry — 13 citations into it; #438 of 547 by trust here, #475 by citations
Whom Luke A. O'Neill trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
- Masahiro Yamamoto
- T. Horng
- R. Medzhitov
- Shintaro Sato
- Shizuo Akira
- Taro Kawai
- Jonathan C. Kagan
- O. Takeuchi
- Katherine A. Fitzgerald
- H. Hemmi
Who trusts Luke A. O'Neill overall
- S. Gordon
- Johanna Napetschnig
- S. Kalimuddin
- C. A. Dinarello
- R. Darveau
- A. Viola
- K. Futosi
- David S. Wishart
- A. Mortha
- C. Porta
Papers from Luke A. O'Neill's perspective
Ordered by how strongly the researchers Luke A. O'Neill trusts endorse each paper. Same corpus, a different order for every researcher.
- Toll-like receptors: critical proteins linking innate and acquired immunity (Nature Immunology)
- Toll-like receptor signalling (Nature reviews. Immunology)
- Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease (Nature)
- Gout-associated uric acid crystals activate the NALP3 inflammasome (Nature)
- A Toll-like receptor recognizes bacterial DNA (Nature)
- Toll-like receptors and innate immunity (Journal of molecular medicine)
- Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin (Journal of Experimental Medicine)
- Negative regulation of Toll-like receptor-mediated immune responses (Nature reviews. Immunology)
- Silica crystals and aluminum salts mediate NALP-3 inflammasome activation via phagosomal destabilization (Nature Immunology)
- Requirement of bic/microRNA-155 for Normal Immune Function (Science)
Their papers
- Activation of the Nlrp3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes (2010) — 1,300 citations
- A long noncoding RNA induced by TLRs mediates both activation and repression of immune response genes (2013) — 885 citations
- Repurposing mitochondria from ATP production to ROS generation drives a pro-inflammatory phenotype in macrophages that depends on succinate oxidation by complex II (2016) — 1,997 citations
- A small molecule inhibitior of the NLRP3 inflammasome is a potential therapeutic for inflammatory diseases (2015) — 2,420 citations
- The Interleukin-1 Receptor/Toll-Like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense (2000) — 764 citations
- Metabolic Reprograming in Macrophage Polarization (2014) — 899 citations
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity (2016) — 765 citations
- Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries. (2000) — 904 citations
- A guiding map for inflammation (2017) — 661 citations
- Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 (2018) — 1,634 citations
- Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice (2018) — 734 citations
- Macrophage Immunometabolism: Where Are We (Going)? (2017) — 1,035 citations
- Mitochondria are the powerhouses of immunity (2017) — 1,002 citations
- Trained immunity: a program of innate immune memory in health and disease (2016) — 2,377 citations
- A guide to immunometabolism for immunologists (2016) — 2,761 citations
- Immunometabolism governs dendritic cell and macrophage function (2016) — 1,528 citations
- Metabolic reprogramming in macrophages and dendritic cells in innate immunity (2015) — 1,714 citations
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages. (2015) — 600 citations
- Pyruvate Kinase M2 regulates Hif-1α activity and IL-1β induction, and is a critical determinant of the Warburg Effect in LPS-activated macrophages (2015) — 953 citations
- Succinate: a metabolic signal in inflammation. (2014) — 657 citations