T. Mak

Molecular Biology · 2000–2018

A researcher in the Science corpus: 30 papers; trusts 17 researchers and is trusted by 13 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 438 citations into it; #4,317 of 17,773 by trust here, #971 by citations
• Cancer Research — 164 citations into it; #406 of 1,780 by trust here, #227 by citations
• Immunology — 156 citations into it; #1,459 of 2,160 by trust here, #229 by citations
• Oncology — 115 citations into it; #972 of 1,698 by trust here, #290 by citations
• Physiology — 39 citations into it
• Cell Biology — 31 citations into it
• Biotechnology — 9 citations into it

Whom T. Mak trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. Bharat B. Aggarwal
2. J. Tschopp
3. W. Kaelin
4. Karen H. Vousden
5. Kate Schroder
6. O. Fernández-Capetillo

Who trusts T. Mak overall

1. Simone Fulda
2. Maria Liberti
3. Y. Fouad

Papers from T. Mak's perspective

Ordered by how strongly the researchers T. Mak trusts endorse each paper. Same corpus, a different order for every researcher.

1. Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death (Science)
2. Non-canonical inflammasome activation targets caspase-11 (Nature)
3. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. (Cancer Cell)
4. Cryopyrin activates the inflammasome in response to toxins and ATP (Nature)
5. The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis (Cell)
6. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury (Nature Chemical Biology)
7. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis (Nature Cell Biology)
8. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. (Cell)
9. RIP3 mediates the embryonic lethality of caspase-8-deficient mice (Nature)
10. A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis. (Developmental Cell)

Their papers

• Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells (2004) — 1,221 citations
• Regulation of cancer cell metabolism (2011) — 4,678 citations
• Modulation of oxidative stress as an anticancer strategy (2013) — 3,257 citations
• Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death (2001) — 1,437 citations
• Two Distinct Pathways Leading to Nuclear Apoptosis (2000) — 800 citations
• Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. (2015) — 901 citations
• Caspase functions in cell death and disease. (2013) — 2,388 citations
• Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. (2001) — 807 citations
• Heat-shock protein 70 antagonizes apoptosis-inducing factor (2001) — 891 citations
• Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. (2002) — 2,488 citations
• Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. (2002) — 723 citations
• Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis (2006) — 1,296 citations
• DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2 (2006) — 824 citations
• Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. (2004) — 695 citations
• Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit (2011) — 1,400 citations
• Cytochrome c: functions beyond respiration (2008) — 1,095 citations
• Pathways of apoptotic and non-apoptotic death in tumour cells (2004) — 1,087 citations
• A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening. (2018) — 630 citations
• TNF and ROS Crosstalk in Inflammation. (2016) — 910 citations
• Regulation of tumour necrosis factor signalling: live or let die (2015) — 936 citations