Caspase functions in cell death and disease.

By David Mcilwain, T. Berger, T. Mak. Cold Spring Harbor Perspectives in Biology, 2013

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Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production (2014, positive): “Caspases are a family of 12 cysteinyl aspartate-specific proteases traditionally classified as inflammatory or apoptotic (McIlwain et al., 2013).”
Bactericidal and Cytotoxic Properties of Silver Nanoparticles (2019, background): “Caspase-3 is the main caspase responsible for apoptosis execution [223].”
Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis (2020, background): “Genetic and biochemical inactivation of caspases has revealed caspase-independent forms of cell death and a more complex relationship between apoptosis and inflammation (33, 58, 59).”
BCL-2 family proteins: changing partners in the dance towards death (2017, background): “homeostasis culminating in the typical biochemical and morphological features of apoptosis.(2) Commitment to the apoptotic dance of death is due in part to”
The molecular machinery of regulated cell death (2019, background): “Caspases are a family of cysteine-dependent aspartate-specific proteases that play a critical role in the regulation of cell death, connecting to development, inflammation, and immunity.(10,11) RCD is therefore categorized into two groups: caspase-dependent (e.”