Pathways of apoptotic and non-apoptotic death in tumour cells

By H. Okada, T. Mak. Nature Reviews. Cancer, 2004

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Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy (2006, background): “Although the signaling pathways and molecules involved in these alternative forms of cell death have not yet exactly been defined, non-caspase proteases such as calpains or cathepsins, lysosomal enzymes or PARP-1 may be involved (Okada and Mak, 2004).”
Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11 (2019, background): “More recent examinations have implicated a number of other forms of regulated cell death, including apoptosis, necroptosis, and autophagy in the response to radiotherapy (8, 9).”
Cell Death Pathways in Photodynamic Therapy of Cancer (2011, background): “The apoptotic process is tightly controlled by various proteins [24,25].”
Tumor resistance to apoptosis (2009, background): “, necrosis, autophagy, mitotic catastrophe and lysosomal cell death.(11) Activation of these nonapoptotic cell death modes presents an alternative approach to induce cell death in apoptosis resistant types of human cancers.”