A. Dinkova-Kostova

Molecular Biology · 2001–2021

A researcher in the Science corpus: 15 papers; trusts 35 researchers and is trusted by 6 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 352 citations into it; #5,582 of 17,773 by trust here, #1,932 by citations
• Physiology — 48 citations into it; #1,509 of 2,276 by trust here, #690 by citations
• Epidemiology — 42 citations into it
• Immunology — 41 citations into it
• Cancer Research — 39 citations into it
• Cell Biology — 37 citations into it
• Oncology — 34 citations into it
• Biochemistry — 32 citations into it; #278 of 547 by trust here, #40 by citations

Whom A. Dinkova-Kostova trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. K. Itoh
2. Masayuki Yamamoto
3. N. Wakabayashi
4. J. Hayes
5. Michael T. McMahon
6. Donna D. Zhang
7. T. Kensler
8. Rafael Radi
9. A. Kobayashi
10. Hozumi Motohashi

Who trusts A. Dinkova-Kostova overall

1. Donna D. Zhang
2. Liam Baird
3. Masayuki Yamamoto
4. A. Kobayashi
5. Makoto Kobayashi
6. H. Forman
7. Q. Ma
8. S. Magesh
9. J. Hayes
10. K. Liby

Papers from A. Dinkova-Kostova's perspective

Ordered by how strongly the researchers A. Dinkova-Kostova trusts endorse each paper. Same corpus, a different order for every researcher.

1. Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2 (Molecular and Cellular Biology)
2. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. (Annual Review of Pharmacology and Toxicology)
3. BTB Protein Keap1 Targets Antioxidant Transcription Factor Nrf2 for Ubiquitination by the Cullin 3-Roc1 Ligase (Molecular and Cellular Biology)
4. Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival (Molecular and Cellular Biology)
5. Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex (Nature)
6. Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress (Molecular and Cellular Biology)
7. Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth. (Cancer Research)
8. Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages* (Journal of Biological Chemistry)
9. Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. (Molecules and Cells)
10. Mechanisms of mitophagy (Nature reviews. Molecular cell biology)

Their papers

• Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants (2002) — 1,958 citations
• Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers (2004) — 1,014 citations
• Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups (2001) — 599 citations
• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) — 3,841 citations
• The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. (2014) — 2,005 citations
• Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress. (2005) — 601 citations
• The cytoprotective role of the Keap1–Nrf2 pathway (2011) — 995 citations
• Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 (2018) — 1,634 citations
• Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease (2015) — 796 citations
• Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases (2019) — 1,270 citations
• Natural products in drug discovery: advances and opportunities (2021) — 4,179 citations
• Oxidative Stress in Cancer (2020) — 1,890 citations
• The emerging role of Nrf2 in mitochondrial function (2015) — 887 citations
• Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders (2010) — 753 citations
• NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector (2010) — 696 citations