Michael T. McMahon

Molecular Biology · 2001–2012

A researcher in the Science corpus: 6 papers; trusts 5 researchers and is trusted by 6 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 85 citations into it; #5,351 of 17,773 by trust here, #3,242 by citations

Whom Michael T. McMahon trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. K. Itoh
2. Donna D. Zhang

Who trusts Michael T. McMahon overall

1. Liam Baird
2. A. Dinkova-Kostova
3. Masayuki Yamamoto
4. J. Hayes
5. Donna D. Zhang
6. A. Kobayashi
7. C. Tonelli
8. Makoto Kobayashi
9. Moon-Il Kang
10. Lauren E Tebay

Papers from Michael T. McMahon's perspective

Ordered by how strongly the researchers Michael T. McMahon trusts endorse each paper. Same corpus, a different order for every researcher.

1. Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2 (Molecular and Cellular Biology)
2. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. (Annual Review of Pharmacology and Toxicology)
3. Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival (Molecular and Cellular Biology)
4. Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. (Advances in Enzyme Regulation)
5. Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy (Proceedings of the National Academy of Sciences of the United States of America)
6. Function and regulation of cullin–RING ubiquitin ligases (Nature reviews. Molecular cell biology)
7. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis (Nature)
8. Increased Protein Stability as a Mechanism That Enhances Nrf2-mediated Transcriptional Activation of the Antioxidant Response Element (Journal of Biological Chemistry)
9. NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer. (TIBS -Trends in Biochemical Sciences. Regular ed)
10. Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition (Nature Cell Biology)

Their papers

• p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription* (2010) — 1,400 citations
• Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression* (2003) — 1,150 citations
• NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer. (2009) — 869 citations
• SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner (2011) — 729 citations
• Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity. (2012) — 642 citations
• The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. (2001) — 701 citations