Jussi Taipale

Molecular Biology · 2000–2020

A researcher in the Science corpus: 24 papers; trusts 7 researchers and is trusted by 15 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 378 citations into it; #2,704 of 17,773 by trust here, #929 by citations
• Genetics — 80 citations into it; #2,754 of 6,854 by trust here, #995 by citations
• Cellular and Molecular Neuroscience — 8 citations into it
• Ecology — 5 citations into it

Whom Jussi Taipale trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. P. Beachy
2. P. Ingham
3. Andrew P. McMahon
4. Baolin Wang
5. M. K. Cooper
6. Elaine Fuchs
7. D. Hanahan
8. T. Xie

Who trusts Jussi Taipale overall

1. P. Beachy
2. R. Nusse
3. P. Ingham
4. Markku Varjosalo
5. James K. Chen
6. S. S. Karhadkar
7. J. Hooper
8. Xiaofeng Qi
9. David M. Berman
10. David M. Gonzalez

Papers from Jussi Taipale's perspective

Ordered by how strongly the researchers Jussi Taipale trusts endorse each paper. Same corpus, a different order for every researcher.

1. The Hedgehog and Wnt signalling pathways in cancer
2. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine (Nature)
3. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. (Genes & Development)
4. Small molecule modulation of Smoothened activity (Proceedings of the National Academy of Sciences of the United States of America)
5. Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. (Development)
6. Patched acts catalytically to suppress the activity of Smoothened (Nature)
7. G Protein-Coupled Receptor Allosterism and Complexing (Pharmacological Reviews)
8. Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function (PLoS Genetics)
9. An LDL-receptor-related protein mediates Wnt signalling in mice (Nature)
10. Vertebrate Smoothened functions at the primary cilium (Nature)

Their papers

• Counting absolute numbers of molecules using unique molecular identifiers (2011) — 993 citations
• DNA-binding specificities of human transcription factors. (2013) — 1,264 citations
• Minimizing the risk of reporting false positives in large-scale RNAi screens (2006) — 480 citations
• The Human Transcription Factors. (2018) — 2,780 citations
• The Hedgehog and Wnt signalling pathways in cancer (2001) — 1,479 citations
• Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities. (2010) — 467 citations
• Impact of cytosine methylation on DNA binding specificities of human transcription factors (2017) — 1,108 citations
• Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo (2010) — 1,163 citations
• Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine (2000) — 1,372 citations
• Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. (2002) — 1,518 citations
• Small molecule modulation of Smoothened activity (2002) — 1,013 citations
• Patched acts catalytically to suppress the activity of Smoothened (2002) — 867 citations
• Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade (2002) — 838 citations
• The interaction landscape between transcription factors and the nucleosome (2017) — 315 citations
• Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. (2013) — 380 citations
• DNA-dependent formation of transcription factor pairs alters their binding specificity (2015) — 529 citations
• CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response (2018) — 1,094 citations
• Conservation of transcription factor binding specificities across 600 million years of bilateria evolution (2015) — 292 citations
• A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding (2014) — 213 citations
• Hedgehog: functions and mechanisms. (2008) — 1,239 citations