P. Beachy

Molecular Biology · 2000–2020

A researcher in the Science corpus: 16 papers; trusts 11 researchers and is trusted by 29 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 110 citations into it; #1,354 of 17,773 by trust here, #1,138 by citations
• Genetics — 25 citations into it; #2,924 of 6,854 by trust here, #1,141 by citations
• Oncology — 24 citations into it

Whom P. Beachy trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. Jussi Taipale
2. G. Sauvageau
3. P. Ingham
4. James K. Chen
5. T. Reya
6. M. K. Cooper
7. David M. Berman
8. D. N. Watkins
9. Baolin Wang
10. S. Morrison

Who trusts P. Beachy overall

1. Markku Varjosalo
2. Jussi Taipale
3. P. Ingham
4. R. Nusse
5. E. Epstein
6. D. N. Watkins
7. J. Hooper
8. Jin Jiang
9. James E. Darnell
10. S. S. Karhadkar

Papers from P. Beachy's perspective

Ordered by how strongly the researchers P. Beachy trusts endorse each paper. Same corpus, a different order for every researcher.

1. The Hedgehog and Wnt signalling pathways in cancer
2. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine (Nature)
3. Small molecule modulation of Smoothened activity (Proceedings of the National Academy of Sciences of the United States of America)
4. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. (Genes & Development)
5. Patched acts catalytically to suppress the activity of Smoothened (Nature)
6. An LDL-receptor-related protein mediates Wnt signalling in mice (Nature)
7. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells (Nature)
8. Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade (Science)
9. Prospective identification of tumorigenic breast cancer cells (Proceedings of the National Academy of Sciences of the United States of America)
10. G Protein-Coupled Receptor Allosterism and Complexing (Pharmacological Reviews)

Their papers

• Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling (2011) — 76 citations
• Minimizing the risk of reporting false positives in large-scale RNAi screens (2006) — 480 citations
• Tissue repair and stem cell renewal in carcinogenesis (2004) — 1,214 citations
• The Hedgehog and Wnt signalling pathways in cancer (2001) — 1,479 citations
• Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris (2018) — 2,436 citations
• Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine (2000) — 1,372 citations
• A Single Cell Transcriptomic Atlas Characterizes Aging Tissues in the Mouse (2020) — 984 citations
• Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. (2002) — 1,518 citations
• Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. (2000) — 1,093 citations
• Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer (2003) — 1,118 citations
• Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours (2003) — 1,318 citations
• Small molecule modulation of Smoothened activity (2002) — 1,013 citations
• Patched acts catalytically to suppress the activity of Smoothened (2002) — 867 citations
• Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade (2002) — 838 citations
• The Hedgehog Response Network: Sensors, Switches, and Routers (2004) — 874 citations
• Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia (2009) — 908 citations