M. C. Simon
Molecular Biology · 2002–2020
A researcher in the Science corpus: 19 papers; trusts 23 researchers and is trusted by 31 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 314 citations into it; #1,807 of 17,773 by trust here, #1,124 by citations
- Cancer Research — 275 citations into it; #98 of 1,780 by trust here, #102 by citations
- Genetics — 69 citations into it; #4,308 of 6,854 by trust here, #1,999 by citations
- Physiology — 64 citations into it; #1,450 of 2,276 by trust here, #776 by citations
- Oncology — 56 citations into it; #1,102 of 1,698 by trust here, #786 by citations
- Cell Biology — 51 citations into it
- Surgery — 40 citations into it
- Immunology — 32 citations into it
Whom M. C. Simon trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
- G. Semenza
- Cheng-Jun Hu
- John D. Gordan
- Shelly C. Lu
- W. Kaelin
- Roland H. Wenger
- M. Schröder
- N. Ferrara
- Jessica A. Bertout
- K. Kondo
Who trusts M. C. Simon overall
- G. Semenza
- Jessica A. Bertout
- Ahmed Mohyeldin
- John D. Gordan
- B. Keith
- R. Guzy
- Peter Friedl
- C. Wigerup
- Cheng-Jun Hu
- J. Mazumdar
Papers from M. C. Simon's perspective
Ordered by how strongly the researchers M. C. Simon trusts endorse each paper. Same corpus, a different order for every researcher.
- Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation (Science)
- HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing (Science)
- Core transcriptional regulatory circuitry in human embryonic stem cells. (Cell)
- Regulation of angiogenesis by hypoxia: role of the HIF system (Nature Medicine)
- Transcription Factor HIF-1 Is a Necessary Mediator of the Pasteur Effect in Mammalian Cells (Molecular and Cellular Biology)
- FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. (Genes & Development)
- Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein* (Journal of Biological Chemistry)
- Transcriptional regulation and transformation by Myc proteins (Nature reviews. Molecular cell biology)
- Myc Stimulates Nuclearly Encoded Mitochondrial Genes and Mitochondrial Biogenesis (Molecular and Cellular Biology)
- Why do cancers have high aerobic glycolysis? (Nature Reviews. Cancer)
Their papers
- Hypoxia-induced energy stress regulates mRNA translation and cell growth. (2006) — 631 citations
- Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. (2005) — 1,511 citations
- Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. (2005) — 2,158 citations
- Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. (2005) — 634 citations
- Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation (2003) — 1,208 citations
- HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation. (2007) — 826 citations
- Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability (2011) — 984 citations
- HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. (2006) — 832 citations
- The impact of O2 availability on human cancer (2008) — 1,373 citations
- HIF1α and HIF2α: sibling rivalry in hypoxic tumor growth and progression (2011) — 1,557 citations
- The N-Terminal Transactivation Domain Confers Target Gene Specificity of Hypoxia-inducible Factors HIF-1α and HIF-2α (2007) — 325 citations
- The role of oxygen availability in embryonic development and stem cell function (2008) — 987 citations
- Hypoxia-induced angiogenesis: good and evil. (2011) — 1,110 citations
- Cellular adaptation to hypoxia through HIFs and beyond (2020) — 1,073 citations
- Glutathione metabolism in cancer progression and treatment resistance (2018) — 1,033 citations
- Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. (2010) — 642 citations
- Hypoxia-inducible factors and the response to hypoxic stress. (2010) — 2,330 citations
- Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. (2003) — 710 citations
- An abundant erythroid protein that stabilizes free α-haemoglobin (2002) — 267 citations