Identification of the haematopoietic stem cell niche and control of the niche size

By Jiwang Zhang, C. Niu, L. Ye, Haiyang Huang, Xi C. He, Wei Tong, J. Ross, J. Haug, Teri Johnson, Jian Q. Feng and 4 more. Nature, 2003

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Revisiting the hallmarks of cancer. (2017, neutral): “[180] Zhang J, Niu C, Ye L, Huang H, He X, Tong WG,”
Stem cell niche: structure and function. (2005, background): “F or p er so na l u se o nl y. ANRV255-CB21-25 ARI 8 September 2005 17:11 The BMP signal plays a role in control of HSC number (Zhang et al. 2003).”
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region (2007, background): “Three days after injection, hCD34 + AML cells were found lining the endosteal surface, the site of the normal hematopoietic stem cell microenvironmental nich”
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. (2006, background): “Hematopoietic stem cells divide infrequently under normal circumstances, and retention of their unique potential for self-renewal may require residence in specialized niches near the endosteal surface (Zhang et al., 2003).”
Hematopoiesis: an evolving paradigm for stem cell biology. (2008, background): “The role of N-cadherin as a mediator of interactions with osteoblasts (Zhang et al., 2003), as well as the prominence of osteoblasts for HSC adherence, have been challenged (Kiel et al.”
Building strong bones: molecular regulation of the osteoblast lineage (2011, background): “Other osteoblast lineage cells contribute to the bone marrow microenvironment, which is essential for haematopoietic stem cell homeostasi”