E. Alnemri

Molecular Biology · 2000–2019

A researcher in the Science corpus: 19 papers; trusts 1 researcher and is trusted by 11 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 419 citations into it; #4,418 of 17,773 by trust here, #587 by citations

Whom E. Alnemri trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. J. Tschopp

Who trusts E. Alnemri overall

1. Kate Schroder

Papers from E. Alnemri's perspective

Ordered by how strongly the researchers E. Alnemri trusts endorse each paper. Same corpus, a different order for every researcher.

1. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation (Cell Death and Differentiation)
2. Cryopyrin activates the inflammasome in response to toxins and ATP (Nature)
3. Gout-associated uric acid crystals activate the NALP3 inflammasome (Nature)
4. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf (Nature)
5. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response (Nature)
6. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. (Molecules and Cells)
7. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis (Nature)
8. Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria (Nature Immunology)
9. Non-canonical inflammasome activation targets caspase-11 (Nature)
10. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. (Molecules and Cells)

Their papers

• Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 (2011) — 2,468 citations
• Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death (2017) — 1,339 citations
• The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation (2007) — 1,055 citations
• A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis (2001) — 1,071 citations
• AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA (2009) — 1,870 citations
• Mechanism of XIAP-mediated inhibition of caspase-9. (2003) — 745 citations
• The PYRIN-CARD Protein ASC Is an Activating Adaptor for Caspase-1* (2002) — 609 citations
• Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1 (2009) — 2,851 citations
• Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction* (2002) — 795 citations
• Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) — 5,732 citations
• Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. (2000) — 1,172 citations
• Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) — 970 citations
• The NLR gene family: a standard nomenclature. (2008) — 933 citations
• Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation* (2012) — 723 citations
• Structural basis of caspase-7 inhibition by XIAP. (2001) — 606 citations
• Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease (2015) — 1,602 citations
• Activation of the IκB Kinases by RIP via IKKγ/NEMO-mediated Oligomerization* (2000) — 176 citations
• Negative regulation of the Apaf-1 apoptosome by Hsp70 (2000) — 860 citations
• Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation (2019) — 729 citations