Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

By D. N. Watkins, David M. Berman, Scott G. Burkholder, Baolin Wang, P. Beachy, S. Baylin. Nature, 2003

1,118 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/614546ee98b62cc187e350b0f5dec31baf3bf5a0

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Citations in the corpus

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours (2003, background): “The recent finding that Hh pathway activity is important for growth of a significant proportion of small-cell lung cancer”
Tumour-initiating cells: challenges and opportunities for anticancer drug discovery (2009, background): “It has been reported that pharmacological inhibitors of Hedgehog signalling display efficacy in various animal models, including those of basal cell carcinoma, medulloblastoma, small-cell lung cancer and pancreatic cance”
Wnt signalling in stem cells and cancer (2005, background): “In an interesting parallel with the influence of the Shh pathway in cancers of the lung and gastrointestinal trac”
The role of the Hedgehog signaling pathway in cancer: A comprehensive review. (2017, background): “Accordingly, Hh signaling is critical for regeneration of the lung epithelium [8], prostate epithelium [10], and exocrine pancreas cells [11].”
Tissue repair and stem cell renewal in carcinogenesis (2004, background): “These cancers include small-cell lung cancer and carcinomas of the oesophagus, stomach, pancreas, biliary tract, and prostat”
Hedgehog Signaling in Development and Cancer (2008, positive): “Consistent with this, Hh signaling is critical for regeneration of the pulmonary epithelium (Watkins et al., 2003), prostate epithelium (Karhadkar et al., 2004), and exocrine pancreas (Fendrich et al., 2008).”
Hedgehog signalling in cancer formation and maintenance (2003, background): “Several recent studies indicate that elevation of the pathway causes cancers in other organs, including the lungs, gastrointestinal tract and pancrea”
Hedgehog: functions and mechanisms. (2008, background): “2004) Small-cell lung cancer (Watkins et al. 2003) Biliary tract cancer (Berman et al.”