Molecular regulation of adipogenesis.

By E. Rosen, B. Spiegelman. Annual Review of Cell and Developmental Biology, 2000

1,339 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/afb084e5d8b8ef3ad955f388d84f32c413bbcdfd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. B. Spiegelman
2. Richard J. Johnson
3. Y. Sautin
4. P. Seale
5. S. Kersten
6. B. McConnell
7. Vincent W. Yang
8. P. Tontonoz

In Molecular Biology

1. B. Spiegelman
2. P. Seale
3. Jiandie D. Lin
4. F. Picard
5. Y. Sautin
6. Richard J. Johnson
7. M. McBurney
8. Wenli Yang

In Physiology

1. B. Spiegelman
2. P. Seale
3. Wenli Yang
4. Jiandie D. Lin
5. Marc Uldry
6. J. St-Pierre
7. L. Guarente
8. Richard J. Johnson

Citations in the corpus

• Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling (2011, background): “Adipogenesis requires the upregulation and transcriptional activity of the nuclear receptor, PPARg in preadipoctyes (Rosen and Spiegelman, 2000), which can be blocked by specific antagonists, bisphenol A diglycidyl ether (BADGE) and GW9662 (Bendixen et al.”
• Developmental origin of fat: tracking obesity to its source. (2007, neutral): “The process of terminal adipocyte differentiation during which preadipocytes mature into adipocytes has been extensively studied in mouse 3T3-L1 and 3T3F442A cell lines and immortalized brown preadipocyte cell lines (Rosen and Spiegelman, 2000).”
• Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States (2006, background): “It is now well established that PPAR is an important transcriptional regulator of adipogenesis (43,44).”
• Mechanisms of nutritional and hormonal regulation of lipogenesis (2001, background): “A comprehensive review on the regulation of adipogenesis has appeared recently (Rosen and Spiegelman, 2000).”
• Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ (2004, background): “3T3-L1 cells undergo one or two mitotic divisions after induction as a prelude to terminal differentiatio”
• The role of FoxO in the regulation of metabolism (2008, background): “Synthetic ligands for this nuclear receptor are used as insulin-sensitizing agents in the treatment of diabetes (Rosen and Spiegelman, 2000).”
• Control of osteoblast function and regulation of bone mass (2003, background): “Transcriptional control of myogenesis and adipogenesis consists of a cascade of transcriptional events driven by a series of transcription factors that control each other's phenotype-specific gene expressio”
• Integration of metabolism and inflammation by lipid-activated nuclear receptors (2008, background): “Examples of target genes are discussed in this section and are reviewed in ref”
• Uric Acid: The Oxidant-Antioxidant Paradox (2008, methodology): “Well-established model of adipocytes differentiated in vitro from the mouse embryonic fibroblast cell line 3T3-L1[46,47] were used to characterize the effects of uric acid.”
• Adipogenesis: from stem cell to adipocyte. (2012, background): “C/EBPα and PPARγ function together as pleiotropic transcriptional activators of the large group of genes that produce the adipocyte phenotype (79, 86, 119).”
• Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. (2006, background): “Although BAT and WAT are functionally distinct, they share certain key transcriptional regulators that mediate their differentiation (Rosen and Spiegelman, 2000).”
• Mammalian Krüppel-Like Factors in Health and Diseases (2010, background): “C/EBPs and are activated in the early phase of adipogenesis, followed by sustained expression of C/EBP and PPAR in the late phase of differentiation and the eventual expression of adipocyte-specific genes (349, 350).”