Adipogenesis: from stem cell to adipocyte.

By Brian J. Galletta, J. Cooper, R. Farese, R. Kaufman, J. Grimes, David I. Stuart. Annual Review of Biochemistry, 2012

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Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications (2019, background): “These stem cells are located in the vascular stroma of adipose tissue as well as in the bone marrow [73]; indeed, bone marrow-derived cells account for approximately 10% of the SAT cell population and are therefore increased by up to 25% in obese people [74].”
Mechanisms and Metabolic Implications of Regional Differences among Fat Depots (2013, background): “…responsiveness, and lipolysis; increased secretion of some adipokines (e.g., leptin) and decreased secretion of others (e.g., PAI-1); and changes in extracellular matrix component production, microRNAs, histones, and chromatin structure (reviewed in Cristancho and Lazar, 2011; Tang and Lane, 2012).”
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts? (2016, background): “Then, the transcription of PPARγ and C/EBPα is activated after the binding of C/EBPβ to regulatory elements in their proximal promoters.(86) Once expressed, C/EBPα maintains the continuous expression of both PPARγ and C/EBPα through binding to their respective C/EBP regulatory elements.”