Developmental origin of fat: tracking obesity to its source.

By S. Gesta, Y. Tseng, C. R. Kahn. Cell, 2007

1,530 citations recorded by the source corpus.

Subfields: Pediatrics, Perinatology and Child Health, Physiology, Surgery

View Paper: https://www.semanticscholar.org/paper/a446afa9c061ddf5ad2b09e927b0aacd2fbb417a

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Citations in the corpus

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch (2014, background): “The location where fat is deposited appears to have a great influence on the likelihood of an individual developing many of the sequelae of obesity (Gesta et al., 2007).”
Mitochondrial complex III ROS regulate adipocyte differentiation (2011, positive): “There are two types of adipose tissue, white adipose tissue (WAT) and brown adipose tissue (BAT) (Gesta et al., 2007).”
The cellular and signaling networks linking the immune system and metabolism in disease (2012, background): “Obesity is the most common cause of insulin resistance, and the current obesity epidemic in the United States and other Western countries is driving a parallel type 2 diabetes epidemi”
Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules (2016, background): “WAT is the most abundant and important energy storage in the form of triglycerides, while BAT is important in energy regulation through thermogenesis, which is important in heat generation in response to cold environments [3].”
Autophagy in mammalian development and differentiation (2010, background): “There is a growing consensus that the ratio of white to brown adipose tissue may influence the development of obesity, which is characterized by an increased mass of white adipose tissu”
Forming functional fat: a growing understanding of adipocyte differentiation (2011, background): “All adipocytes, along with osteoblasts, myocytes and chondrocytes, differentiate from mesenchymal stem cells (MSCs”
Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders (2016, background): “The adipose tissue is distributed throughout the body and is capable of expanding to accommodate excess energy in the form of accumulated lipids, characteristics distinguishing the adipose tissue from other organs and tissues (8).”
Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling (2014, background): “Obesity develops when energy intake exceeds energy expenditure (1) and is principally characterized by excess adipose tissue (2,3).”