Resolution of inflammation: the beginning programs the end

By C. Serhan, J. Savill. Nature Immunology, 2005

2,559 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/ad9a6bd18987a8e58c23a498a05bb99e7aaedde2

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Citations in the corpus

Inflammation 2010: new adventures of an old flame. (2010, background): “This switch, in turn, orchestrates a transition from neutrophil to monocyte recruitment that results in clearance of the dead cells and other debris and initiation of tissue repair at the affected site (Serhan and Savill, 2005).”
Control of chemokine-guided cell migration by ligand sequestration. (2008, background): “Different mechanisms that promote clearing of the attractive signal were identified, and these allow efficient resolution and reduction of tissue damage (reviewed in Hansell and Nibbs, 2007; Mantovani et al., 2006; Serhan and Savill, 2005).”
Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis (2007, background): “These can then be converted to bioactive intermediaries such as eicosanoids from arachidonic acid, neuroprotectins from DHA, D series resolvins from DHA and E series resolvins from EP”
Pro-resolving lipid mediators are leads for resolution physiology (2014, background): “Lipoxin A(4) and benzo-lipoxin A(4) attenuate experimental renal fibrosis.”
Resolvin E1 Selectively Interacts with Leukotriene B4 Receptor BLT1 and ChemR23 to Regulate Inflammation1 (2007, background): “Most inflammatory challenges are self-limited in healthy subjects, implicating the existence of endogenous circuits for anti-inflammation and proresolution mediators that are operative during the temporal events of host defense and inflammation (2).”
Beneficial suicide: why neutrophils die to make NETs (2007, background): “Apoptotic neutrophils are swiftly removed by macrophages, preventing the release of neutrophil proteins that can cause tissue damag”
Resolution of inflammation: state of the art, definitions and terms (2006, background): “1C), may lead to prolonged inflammation and the inability for the tissue to return to homeostasis (26) and complete the full life-cycle per se of the neutrophils and mononuclear cells recruited to the tissue.”
Differential Macrophage Programming in the Tumor Microenvironment (2012, positive): “In this context, tissue-resident macrophages assist with combating infection [1, 2], resolving acute inflammation [3], and in regulating metabolic response to tissue stress [4, 5].”
NF-κB and the immune response (2006, background): “It is believed that reversal of inflammation is an active process that is as complex as the inflammatory response itself, and involves numerous pathways that are not all directly relevant to NF-kB (Serhan and Savill, 2005).”
Cellular and molecular mechanisms of skin wound healing (2024, neutral): “Pro-resolving activities include the removal of apoptotic neutrophils and the cessation of inflammatory signalling and eicosanoid production 119 .”
Annexin A1 and glucocorticoids as effectors of the resolution of inflammation (2009, background): “The concept that inflammation is resolved in a time- and space-specific manner is emerging, such that different outcomes can be produced according to the stage or site at which a given pathway or mediator becomes operativ”
Role of Antioxidants and Natural Products in Inflammation (2016, background): “Protectins and resolvins which constitute another class of lipid marker in addition to TGF-β and other growth factors generated from macrophages also have a vital role in the resolution of inflammation including the foundation of tissue repair [9, 10].”