Reactive oxygen species in tumor progression.

By P. Storz. Frontiers in Bioscience, 2005

953 citations recorded by the source corpus.

Subfields: Molecular Biology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/a2b3287be3a0b8f6472d79daef3f10e1be008902

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. G. Barrera
2. M. Valko
3. Subash C. Gupta
4. S. Heasman
5. Wen-Sheng Wu
6. Geou-Yarh Liou
7. A. Ridley
8. I. Shimomura

In Organic Chemistry

1. M. Valko
2. Wen-Sheng Wu
3. G. Barrera
4. A. Ridley
5. J. Fiedor
6. Eyal Gottlieb
7. Geou-Yarh Liou
8. M. Matsuda

Citations in the corpus

• Oxidative stress, DNA methylation and carcinogenesis. (2008, background): “Finally, metastasis is an integral part of tumor progression during which ROS have been documented to play a major role [17–19].”
• Reactive oxygen species in cancer (2010, background): “Email: storz.peter@mayo.edu Keywords: Oxidative stress , reactive oxygen species , cancer , signal transduction Abbreviations: 5-LOX, 5-Lipoxygenase; AP-1, activating protein-1; Ask-1, apoptosis signal-regulating kinase-1; BER, base excision repair; BITC, benzyl isothiocyanate; BPQ, benzo(a)pyrene q”
• Potential Role of Carotenoids as Antioxidants in Human Health and Disease (2014, background): “Hydrogen peroxide is regarded as a mild oxidant; however, it is able to oxidize cysteine residues in proteins [53].”
• Free radicals and antioxidants in normal physiological functions and human disease. (2007, background): “ROS can thus lay a very important physiological role as secondary hemistry & Cell Biology 39 (2007) 44–84 53 messengers (Lowenstein, Dinerman, & Snyder, 1994; Storz, 2005).”
• Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. (2005, background): “[11] Storz P.”
• Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems (2017, background): “On one hand, an overproduction of ROS is associated with chronic inflammation and can also induce DNA damage increasing the mutation rate and the probability that cells undergo oncogenic transformation [73].”
• The signaling mechanism of ROS in tumor progression (2007, background): “Recently, the involvement of ROS signaling in tumor metastasis was highlighted [15, 16].”
• Mammalian Rho GTPases: new insights into their functions from in vivo studies (2008, background): “These results could implicate Rac isoforms in ROS-induced DNA damage in human diseases, for example cance”
• Antioxidant and antimicrobial activities of rosemary extracts linked to their polyphenol composition (2006, background): “They also have an important role in preventing a variety of diseases and aging because they inhibit or delay the oxidation process by blocking the initiation or propagation of oxidizing chain reactions [1,2].”
• Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. (2008, background): “In addition to regulating tumor growth and survival, ROS also participate in those mechanisms that are associated with the tumor metastasis, such as migration and invasion (45).”
• Mitochondrial tumour suppressors: a genetic and biochemical update (2005, background): “Whereas the role of ROS in inducing apoptosis is fairly well established, it will be important to further investigate the potential role of redox stress in promoting tumorigenesis in general and in SDH-deficient tumours in particula”
• Increased oxidative stress in obesity: implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer. (2013, background): “Increased ROS are lso involved in tumor proliferation by ligandndependent transactivation of receptor tyrosine inase [105,108], promoting the invasion or metasasis of cancer cells [109—111].”
• Oxidative stress, inflammation, and cancer: how are they linked? (2010, background): “contribute to tumor development through the regulation of cellular proliferation, angiogenesis, and metastasis [160].”
• Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy (2012, background): “ROS can elicit a broad spectrum of responses depending on the magnitude of the level, the duration of exposure, the localization, and the nature of ROS involved [54].”