The signaling mechanism of ROS in tumor progression

By Wen-Sheng Wu. Cancer Metastasis Review, 2007

754 citations recorded by the source corpus.

Subfields: Biotechnology, Cancer Research, Oncology

View Paper: https://www.semanticscholar.org/paper/5b657e3a57128a7b96da3b6e9db4e1fe1ce64144

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biotechnology

1. Yongqiang Chen
2. Geou-Yarh Liou
3. M. Azad
4. S. Gibson
5. P. Storz
6. G. Barrera

In Cancer Research

1. G. Barrera
2. Yongqiang Chen
3. S. Gibson
4. M. Azad
5. Peng Huang
6. Geou-Yarh Liou
7. B. A. Hocevar
8. P. Storz

In Oncology

1. Peng Huang
2. Yongqiang Chen
3. Geou-Yarh Liou
4. B. A. Hocevar
5. M. Azad
6. S. Gibson
7. P. Storz
8. L. Kamendulis

Citations in the corpus

• Regulation of reactive oxygen species generation in cell signaling (2011, background): “TPA-induced ROS production is known to be mediated by NADPH oxidase and/or mitochondria and ROS induced by TPA are associated with tumor cell invasion (Frost et al., 1994; Wu, 2006).”
• Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? (2009, background): “Because the increase of ROS in cancer cells may play an important part in the initiation and progression of cance”
• Oxidative Stress and Oxidative Damage in Carcinogenesis (2010, background): “In addition, ROS may activate MAP kinases via the PKC pathway (Wu 2006).”
• ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells (2019, background): “UPR triggers ROS production, and ROS, in turn, can promote ER stress [65, 66].”
• Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy (2012, neutral): “First, ROS play an important role in the initiation and progression of cancer (38, 45, 268, 332).”
• Reactive oxygen species in cancer (2010, background): “Other ROS-regulated genes relevant to EMT are E-cadherin, integrins and MMPs [173].”
• Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment (2009, positive): “Recently, ROS have been identified as signaling molecules in various pathways regulating cell survival and cell death (116).”
• Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy (2012, background): “Several experimental results demonstrated that the increase of ROS in cancer cells may play an important role in the initiation and progression of cancer [107, 108] such that intrinsic oxidative stress is often viewed as an adverse event.”
• Oxidative Stress in Aging Human Skin (2015, background): “This release of calcium then activates PKC (protein kinase C) which is also involved in cell migration, apoptosis, proliferation and cytoskeletal reorganisation [298,323,324].”