The interaction between bacteria and bile.

By M. Begley, C. Gahan, C. Hill. FEMS Microbiology Reviews, 2005

1,765 citations recorded by the source corpus.

Subfields: Food Science, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8109c4a421c41c04426ab9d5b7bc1e5a31b446ae

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Food Science

1. H. Wexler
2. S. Lebeer
3. C. Hill
4. A. H-Kittikun
5. S. Mortazavi
6. Reza Mokarram
7. F. Shahidi
8. David S. Wishart

In Infectious Diseases

1. C. Hill
2. S. Lebeer
3. H. Wexler
4. J. Vanderleyden

In Molecular Biology

1. Almut Heinken
2. David S. Wishart
3. A. H-Kittikun
4. L. Piddock
5. Efstathios Z Panagou
6. G. Gibson
7. Julian Parkhill
8. Ines Thiele

Citations in the corpus

• Low Concentrations of Bile Salts Induce Stress Responses and Reduce Motility in Bacillus cereus ATCC 14570 (2007, background): “that bile salts, on entering cells, cause misfolding of proteins due to the detergent properties of bile salts (7).”
• Metabolomics for Investigating Physiological and Pathophysiological Processes. (2019, background): “The TGR5mediated changes of the gut’s immune response mean that bile acids can influence the gut’s microbial composition (36).”
• Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms (2009, neutral): “bilizing the bacterial cell membrane (22).”
• Clinically Relevant Chromosomally Encoded Multidrug Resistance Efflux Pumps in Bacteria (2006, background): “jejuni that mutants lacking components of the AcrAB-TolC pump or the CmeABC pump are hypersusceptible to bile and bile salts (natural antimicrobial substances produced in the avian and mammalian gut as an antimicrobial defense to bacterial challenge) and that mutants that overexpress components of t”
• The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome (2006, background): “The conjugated biles can be subjected to various modifications by members of the intestinal microflora to form a number of secondary bile acid”
• Role of bile acids and bile acid receptors in metabolic regulation. (2009, background): “The intensive interactions between intestinal flora and BAs and their implications have been the subject of excellent recent reviews (16, 257).”
• Probiotic potential of lactic acid bacteria isolated from chicken gastrointestinal digestive tract (2009, background): “membrane lipids and cause dissociation of integral membrane proteins resulting in the leakage of cell contents and cell death (Begley et al. 2005).”
• Gut microbiota functions: metabolism of nutrients and other food components (2017, background): “These characteristics include detergent effects on bacterial cell membranes and the ability to induce DNA damage and disruption to protein structures [58–60].”
• Clostridium scindens baiCD and baiH genes encode stereo-specific 7α/7β-hydroxy-3-oxo-Δ4-cholenoic acid oxidoreductases (2008, background): “Detoxification does not appear to be the function of the bile acid 7α/β-dehydroxylating pathways, but rather the substrates appear to serve as electron sinks to enhance fermentation (2,14).”
• Bile Salt Hydrolase Activity in Probiotics (2006, background): “BB, Bifidobacterium bifidum (AAT11513 [50]); BL, Bifidobacterium longum (AAF67801 [88]); CP, Clostridium perfringens (P54965 [14]); LA, Lactobacillus acidophilus (AAD03709 [31]); LJ, Lactobacillus johnsonii (AAG22541 [31]); LP, Lactobacillus plantarum (AAB24746 [13]); LM, Listeria monocytogenes (CAD”
• Bacteroides: the Good, the Bad, and the Nitty-Gritty (2007, background): “The detergent activity of bile salts permeabilizes bacterial membranes and can eventually lead to membrane collapse and cell damage (16, 34, 70).”
• Genes and Molecules of Lactobacilli Supporting Probiotic Action (2008, background): “Given that the liver excretes approximately 1 liter of bile each day into the small intestine, exposure to bile represents another challenge for bacteria entering the GIT (17).”
• The influence of multi stage alginate coating on survivability of potential probiotic bacteria in simulated gastric and intestinal juice (2009, background): “The presence of food in the intestine may also affect survival as bacteria may not be exposed to bile in certain microenvironments created by the food matrix or food constituents may even bind bile acids and prevent them from exerting toxicity (Begley et al., 2005).”