R. J. Lefkowitz

Molecular Biology · 2000–2018

A researcher in the Science corpus: 28 papers; trusts 10 researchers and is trusted by 18 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 117 citations into it; #1,916 of 17,773 by trust here, #1,460 by citations
• Cellular and Molecular Neuroscience — 85 citations into it; #491 of 2,998 by trust here, #200 by citations
• Oncology — 14 citations into it; #1,355 of 1,698 by trust here, #1,023 by citations
• Spectroscopy — 13 citations into it
• Computational Theory and Mathematics — 10 citations into it; #11,379 of 12,182 by trust here, #1,133 by citations
• Cardiology and Cardiovascular Medicine — 6 citations into it; #616 of 906 by trust here, #232 by citations

Whom R. J. Lefkowitz trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. Sudha K. Shenoy
2. L. Luttrell
3. Seungkirl Ahn
4. Kunhong Xiao
5. S. Rajagopal
6. M. Caron
7. David J. Katzmann

Who trusts R. J. Lefkowitz overall

1. Sudha K. Shenoy
2. Éric Reiter
3. Brian K. Kobilka
4. S. Rajagopal
5. R. Gainetdinov
6. J. Beaulieu
7. Seungkirl Ahn
8. Kunhong Xiao
9. S. Dewire
10. A. Hanyaloglu

Papers from R. J. Lefkowitz's perspective

Ordered by how strongly the researchers R. J. Lefkowitz trusts endorse each paper. Same corpus, a different order for every researcher.

1. Regulation of Receptor Fate by Ubiquitination of Activated β2-Adrenergic Receptor and β-Arrestin (Science)
2. Seven-Transmembrane Receptor Signaling Through β-Arrestin (Science's STKE)
3. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. (Analytical Chemistry)
4. Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics* (Molecular & Cellular Proteomics)
5. ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage (Science)
6. A probability-based approach for high-throughput protein phosphorylation analysis and site localization (Nature Biotechnology)
7. Receptor downregulation and multivesicular-body sorting (Nature reviews. Molecular cell biology)
8. β-Arrestin–Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated Erk1/2 (Journal of Cell Biology)
9. Roles of G‐protein‐coupled receptor dimerization (EMBO Reports)
10. Ubiquitin-binding domains (Nature reviews. Molecular cell biology)

Their papers

• Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors (2011) — 598 citations
• Teaching old receptors new tricks: biasing seven-transmembrane receptors (2010) — 842 citations
• Regulation of Receptor Fate by Ubiquitination of Activated β2-Adrenergic Receptor and β-Arrestin (2001) — 661 citations
• Transduction of Receptor Signals by ß-Arrestins (2005) — 1,247 citations
• Seven-transmembrane-spanning receptors and heart function (2002) — 1,004 citations
• Seven-Transmembrane Receptor Signaling Through β-Arrestin (2005) — 158 citations
• Activation-dependent Conformational Changes in β-Arrestin 2* (2004) — 137 citations
• Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds (2001) — 899 citations
• β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3 (2000) — 858 citations
• Desensitization of G protein-coupled receptors and neuronal functions. (2004) — 889 citations
• Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2 (2003) — 639 citations
• Multiple ligand-specific conformations of the β2-adrenergic receptor. (2011) — 253 citations
• μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence (2000) — 828 citations
• β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor* (2006) — 674 citations
• β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC (2000) — 194 citations
• β-Arrestins and Cell Signaling (2007) — 1,257 citations
• Multifaceted roles of β-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling (2003) — 445 citations
• Distinct Phosphorylation Sites on the β2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin (2011) — 622 citations
• GRKs and β-arrestins: roles in receptor silencing, trafficking and signaling (2006) — 606 citations
• Trafficking Patterns of β-Arrestin and G Protein-coupled Receptors Determined by the Kinetics of β-Arrestin Deubiquitination* (2003) — 231 citations