Brian K. Kobilka

Molecular Biology · 2002–2020

A researcher in the Science corpus: 29 papers; trusts 27 researchers and is trusted by 18 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 271 citations into it; #2,652 of 17,773 by trust here, #574 by citations
• Cellular and Molecular Neuroscience — 134 citations into it; #616 of 2,998 by trust here, #14 by citations
• Materials Chemistry — 54 citations into it
• Computational Chemistry & Drug Discovery — 33 citations into it; #237 of 425 by trust here, #371 by citations
• Computational Theory and Mathematics — 21 citations into it; #7,265 of 12,182 by trust here, #787 by citations
• Nutrition and Dietetics — 13 citations into it
• Oncology — 8 citations into it
• Organic Chemistry — 6 citations into it

Whom Brian K. Kobilka trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. John J. Irwin
2. R. J. Lefkowitz
3. Brian K. Shoichet
4. S. Rasmussen
5. Robert Fredriksson
6. Michael M. Mysinger
7. S. Angers
8. A. Kruse
9. Garrett M. Morris
10. D. Rosenbaum

Who trusts Brian K. Kobilka overall

1. Vsevolod Katritch
2. Vadim Cherezov
3. D. Rosenbaum
4. S. Rasmussen
5. L. Ferreira
6. Raymond C. Stevens
7. Veronica Salmaso
8. Christian A. Bippes
9. Ron O. Dror
10. Bryan L. Roth

Papers from Brian K. Kobilka's perspective

Ordered by how strongly the researchers Brian K. Kobilka trusts endorse each paper. Same corpus, a different order for every researcher.

1. Crystal Structure of Rhodopsin: A G‐Protein‐Coupled Receptor (ChemBioChem)
2. Conformational complexity of G-protein-coupled receptors. (TIPS - Trends in Pharmacological Sciences)
3. Crystal structure of opsin in its G-protein-interacting conformation (Nature)
4. All-atom empirical potential for molecular modeling and dynamics studies of proteins.
5. Roles of G‐protein‐coupled receptor dimerization (EMBO Reports)
6. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor (Nature)
7. Regulation of GPCRs by endocytic membrane trafficking and its potential implications. (Annual Review of Pharmacology and Toxicology)
8. Structure and Function of an Irreversible Agonist-β2 Adrenoceptor complex (Nature)
9. MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes (Nucleic Acids Res.)
10. Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders (Nature reviews. Drug discovery)

Their papers

• Crystal structure of the human β2 adrenergic G-protein-coupled receptor (2007) — 1,633 citations
• High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor (2007) — 2,512 citations
• Structure of the δ-opioid receptor bound to naltrindole (2012) — 630 citations
• Conformational complexity of G-protein-coupled receptors. (2007) — 710 citations
• Crystal structure of the μ-opioid receptor bound to a morphinan antagonist (2012) — 1,392 citations
• Crystal Structure of the β2Adrenergic Receptor-Gs protein complex (2011) — 2,924 citations
• Structure–based discovery of opioid analgesics with reduced side effects (2016) — 863 citations
• GPCR Engineering Yields High-Resolution Structural Insights into β2-Adrenergic Receptor Function (2007) — 1,308 citations
• Structure and Function of an Irreversible Agonist-β2 Adrenoceptor complex (2011) — 766 citations
• Structure and Dynamics of the M3 Muscarinic Acetylcholine Receptor (2012) — 789 citations
• Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist (2012) — 821 citations
• Structure of a nanobody-stabilized active state of the β2 adrenoceptor (2011) — 1,689 citations
• Structural insights into differences in G protein activation by family A and family B GPCRs (2020) — 132 citations
• Structure-based drug screening for G-protein-coupled receptors. (2012) — 278 citations
• A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein (2007) — 691 citations
• The dynamic process of β2-adrenergic receptor activation (2013) — 757 citations
• Activation and allosteric modulation of a muscarinic acetylcholine receptor (2013) — 884 citations
• Functional Selectivity and Classical Concepts of Quantitative Pharmacology (2007) — 1,147 citations
• Structural insights into μ-opioid receptor activation (2015) — 833 citations
• Structural insights into the dynamic process of β2-adrenergic receptor signaling (2015) — 640 citations