S. Gaffen

Immunology · 2007–2019

A researcher in the Science corpus: 7 papers; trusts 17 researchers and is trusted by 7 researchers here, as inferred from the citation graph.

Subfields

• Immunology — 211 citations into it; #508 of 2,160 by trust here, #865 by citations
• Pathology and Forensic Medicine — 58 citations into it; #80 of 414 by trust here, #206 by citations
• Oncology — 42 citations into it
• Rheumatology — 18 citations into it

Whom S. Gaffen trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. I. McInnes
2. Georg Schett
3. D. Cua
4. M. McGeachy
5. L. Harrington
6. Xuexian O. Yang
7. Yi Chen
8. L. Steinman
9. Paul R. Mangan
10. E. Bettelli

Who trusts S. Gaffen overall

1. D. Cua
2. Nilesh Amatya
3. Adriana Rendon
4. M. McGeachy
5. K. Futosi
6. C. Rosales
7. A. Garg

Papers from S. Gaffen's perspective

Ordered by how strongly the researchers S. Gaffen trusts endorse each paper. Same corpus, a different order for every researcher.

1. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
2. New IL-17 Family Members Promote Th1 or Th2 Responses in the Lung: In Vivo Function of the Novel Cytokine IL-251 (Journal of Immunology)
3. Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17*
4. Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense (Journal of Experimental Medicine)
5. Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation (Journal of Experimental Medicine)
6. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells (Nature Immunology)
7. Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages (Nature Immunology)
8. Induction of intestinal Th17 cells by segmented filamentous bacteria (Cell)
9. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
10. Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system (Nature Immunology)

Their papers

• The IL-17 family of cytokines in health and disease (2019) — 1,260 citations
• IL-17 Signaling: The Yin and the Yang (2017) — 726 citations
• IL-23-IL-17 immune axis: Discovery, Mechanistic Understanding, and Clinical Testing (2014) — 1,483 citations
• Interleukin‐17 and its target genes: mechanisms of interleukin‐17 function in disease (2010) — 929 citations
• Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis (2009) — 1,050 citations
• Structure and signalling in the IL-17 receptor superfamily (2009) — 1,388 citations
• IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge (2007) — 1,498 citations