J. Pouysségur

Molecular Biology · 2000–2016

A researcher in the Science corpus: 14 papers; trusts 22 researchers and is trusted by 23 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 190 citations into it; #1,757 of 17,773 by trust here, #1,833 by citations
• Cancer Research — 143 citations into it; #135 of 1,780 by trust here, #229 by citations
• Physiology — 52 citations into it
• Oncology — 38 citations into it
• Cell Biology — 25 citations into it
• Genetics — 18 citations into it; #4,007 of 6,854 by trust here, #2,249 by citations
• Biochemistry — 7 citations into it
• Pharmacology — 5 citations into it

Whom J. Pouysségur trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. G. Semenza
2. Jung-whan Kim
3. Robert A. Gatenby
4. N. Ferrara
5. J. P. Thiery
6. R. Fukuda
7. P. Vaupel
8. R. Cardone
9. A. Halestrap
10. Guido Kroemer

Who trusts J. Pouysségur overall

1. Guido Kroemer
2. G. Semenza
3. J. Chiche
4. D. Hanahan
5. Anthony Kar Lun Leung
6. Ji Luo
7. Claudiu T. Supuran
8. A. Jetten
9. Dai Fukumura
10. M. Brahimi-Horn

Papers from J. Pouysségur's perspective

Ordered by how strongly the researchers J. Pouysségur trusts endorse each paper. Same corpus, a different order for every researcher.

1. Why do cancers have high aerobic glycolysis? (Nature Reviews. Cancer)
2. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation (Science)
3. Targeting HIF-1 for cancer therapy (Nature Reviews. Cancer)
4. Akt Stimulates Aerobic Glycolysis in Cancer Cells (Cancer Research)
5. Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. (Cancer Cell)
6. p53 Regulates Mitochondrial Respiration (Science)
7. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. (Cancer Cell)
8. Deregulation of Glucose Transporter 1 and Glycolytic Gene Expression by c-Myc* (Journal of Biological Chemistry)
9. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. (Cell Metabolism)
10. Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer (Nature Medicine)

Their papers

• Tumor cell metabolism: cancer's Achilles' heel. (2008) — 2,297 citations
• Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains (2009) — 1,454 citations
• Hypoxia signalling in cancer and approaches to enforce tumour regression (2006) — 1,720 citations
• HIF prolyl‐hydroxylase 2 is the key oxygen sensor setting low steady‐state levels of HIF‐1α in normoxia (2003) — 1,412 citations
• JunD reduces tumor angiogenesis by protecting cells from oxidative stress. (2004) — 598 citations
• Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. (2009) — 728 citations
• Hypoxia-induced autophagy: cell death or cell survival? (2010) — 615 citations
• The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition (2007) — 1,152 citations
• Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity (2006) — 706 citations
• Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells. (2000) — 670 citations
• ERK implication in cell cycle regulation. (2007) — 784 citations
• Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer (2009) — 642 citations
• Hypoxia and cancer (2007) — 845 citations
• LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells. (2016) — 1,711 citations