D. Alessi

Molecular Biology · 2000–2020

A researcher in the Science corpus: 18 papers; trusts 7 researchers and is trusted by 18 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 180 citations into it; #1,934 of 17,773 by trust here, #1,008 by citations
• Surgery — 25 citations into it; #785 of 1,106 by trust here, #396 by citations
• Genetics — 19 citations into it

Whom D. Alessi trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. K. Inoki
2. D. Hardie
3. D. Guertin

Who trusts D. Alessi overall

1. D. Hardie
2. David M. Sabatini
3. M. Laplante
4. R. Shaw
5. N. Tonks
6. D. Trachootham
7. R. A. Saxton
8. T. Balla
9. R. Loewith
10. G. Steinberg

Papers from D. Alessi's perspective

Ordered by how strongly the researchers D. Alessi trusts endorse each paper. Same corpus, a different order for every researcher.

1. AMP‐activated protein kinase: the energy charge hypothesis revisited (Bioessays)
2. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? (Journal of Cell Science)
3. The Protein Kinase Complement of the Human Genome (Science)
4. Specificity and mechanism of action of some commonly used protein kinase inhibitors. (Biochemical Journal)
5. Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
6. AMPK phosphorylation of raptor mediates a metabolic checkpoint. (Molecules and Cells)
7. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. (Developmental Cell)
8. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. (Biochemical Journal)
9. Very high risk of cancer in familial Peutz-Jeghers syndrome. (Gastroenterology)
10. The phosphoinositide 3-kinase pathway. (Science)

Their papers

• Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade (2003) — 1,571 citations
• Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase (2001) — 854 citations
• LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1 (2004) — 1,432 citations
• mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). (2008) — 933 citations
• Metformin and reduced risk of cancer in diabetic patients (2005) — 2,407 citations
• PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? (2001) — 1,181 citations
• LKB1-dependent signaling pathways. (2006) — 810 citations
• PDK1, the master regulator of AGC kinase signal transduction. (2004) — 870 citations
• The nuts and bolts of AGC protein kinases (2010) — 1,350 citations
• The selectivity of protein kinase inhibitors: a further update. (2007) — 2,647 citations
• New Users of Metformin Are at Low Risk of Incident Cancer (2009) — 1,086 citations
• Activation of the tumour suppressor kinase LKB1 by the STE20‐like pseudokinase STRAD (2003) — 409 citations
• Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65 (2014) — 748 citations
• Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis (2005) — 647 citations
• The PI3K-PDK1 connection: more than just a road to PKB. (2000) — 1,686 citations
• Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. (2020) — 659 citations
• Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases (2016) — 918 citations
• PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65 (2012) — 915 citations