Neurotechnique Induction of Midbrain Dopaminergic Neurons from ES Cells by Stromal Cell-Derived Inducing Activity

By H. Kawasaki, Kenji Mizuseki, Satomi Nishikawa, S. Kaneko, Y. Kuwana, S. Nakanishi, Shin-ichi Nishikawa, Y. Sasai, Kyowa Hakko Kogyo. 2000

1,293 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/fec8d0783dcc79ec2566dd175b9847b04a978d7c

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Citations in the corpus

Embryo-derived stem cells: of mice and men. (2001, background): “1996) and to produce dopaminergic neurons (Kawasaki et al. 2000).”
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 (2008, background): “Two factor–induced iPS cells were successfully differentiated into neurons (ectoderm derivative) co-expressing βIII-tubulin and TH (tyrosine hydroxylase), the latter being a marker for dopaminergic neurons, beating cardiomyocytes (mesoderm derivative) and definitive endoderm as well as endoderm-deri”
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. (2007, methodology): “We seeded human iPS cells on PA6 feeder layer and maintained them under differentiation conditions for 2 weeks (Kawasaki et al., 2000).”
Directed differentiation of embryonic stem cells into motor neurons. (2002, methodology): “ES cells possess the capacity to generate neurons and glial cells, which in some instances express markers characteristic of specific classes of neurons, for example, midbrain dopaminergic neurons (Kawasaki et al., 2000; Lee et al., 2000).”
A MicroRNA Feedback Circuit in Midbrain Dopamine Neurons (2007, methodology): “Two predominant methods have been established for ES cell development: 1) an embryoid body- (EB)based protocol (Lee et al. 2000) that involves detachment of ES cells from an adherent surface, growth as cell aggregates in suspension, and subsequent reattachment; and 2) a coculture-based protocol that”
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors (2011, background): “Coculture of these iPSCs with PA6 feeder cells resulted in the generation of dopaminergic neurons (ectoderm derivatives) that were positive for βIII tubulin and tyrosine hydroxylase (27) (Fig.”
Functional engraftment of human ES cell–derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes (2006, methodology): “Coculture with stromal feeder cells and striatal astrocytes has thus been used to accentuate dopaminergic neuronal production in vitro”
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture (2003, background): “or by coculture with a particular stromal cell line, PA6 (ref”
Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. (2004, methodology): “Primer sequences and precise conditions are described elsewhere (1, 17, 19, 30).”
Specification of motoneurons from human embryonic stem cells (2005, methodology): “, have been induced in vitro to adopt a neuroectodermal fat”
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. (2008, background): “Early methods to direct the differentiation of ESCs to neural fates used treatment with retinoic acid (Bain et al., 1995), sequential culture in serum and serum-free media (Okabe et al., 1996), or coculture with specific stromal cell lines such as PA6 (Kawasaki et al., 2000).”