Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development.

By Charles E. Murry, G. Keller. Cell, 2008

1,764 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/1ba595d2d3531f5d9bbcbeeefc7af7f1e0365855

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Surgery

G. Keller

Citations in the corpus

Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. (2011, background): “applications of PSC-derived cell types to become a reality, strategies need to be developed that promote the efficient and reproducible differentiation of both ESCs and iPSCs to the cardiac lineage (Murry and Keller, 2008).”
Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. (2014, background): “Despite the successful achievement of various types of tissues from pluripotent stem cells (PSCs), kidney generation in vitro has remained a challenge for developmental biology and regenerative medicine (Murry and Keller, 2008; Williams et al., 2012).”
Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage (2012, neutral): “This process involves specification of pluripotent cells tomesodermal and cardiac precursors prior to terminal differentiation (Evans et al., 2010; Murry and Keller, 2008; Srivastava, 2006).”
Making muscle: skeletal myogenesis in vivo and in vitro (2017, neutral): “2A) (Fan and Tessier-Lavigne, 1994; Johnson et al., 1994; Murtaugh et al., 1999).”
Ethical and Safety Issues of Stem Cell-Based Therapy (2018, background): “When undifferentiated hESCs are transplanted, teratomas, tumors that contain all three germ layers, could develop [Figure 1] [15].”
Braveheart, a long non-coding RNA required for cardiovascular lineage commitment (2013, background): “…as Xist and Neat1 have undergone rapid sequence evolution while preserving their functional roles Cell 152, 570–583, January 31, 2013 ª2013 Elsevier Inc. 577 (legend continued on next page) 578 Cell 152, 570–583, January 31, 2013 ª2013 Elsevier Inc. (Clemson et al., 2009; Nesterova et al., 2001).”
Disease-specific induced pluripotent stem (iPS) cells (2008, neutral): “Human embryonic stem cells isolated from excess embryos from in vitro fertilization clinics represent an immortal propagation of pluripotent cells that theoretically can generate any cell type within the human body (Lerou et al., 2008; Murry and Keller, 2008).”