Mitochondrial and peroxisomal β-oxidation capacities in various tissues from Atlantic salmon Salmo salar.

By FrØyland, Lie, Bergé. 2000

136 citations recorded by the source corpus.

In order to investigate the capacities of different tissues to oxidize fatty acids, total β-oxidation (mitochondrial and peroxisomal) of [1–14C]palmitoyl-CoA was determined in liver and red- and white muscle from adult and juvenile Atlantic salmon Salmo salar. By including potassium cyanide (KCN) in the assay medium, it was possible to differentiate between mitochondrial and peroxisomal β-oxidation capacities. Mitochondrial β-oxidation dominated in all tissues except in livers from juvenile fish where the peroxisomal β-oxidation dominated. In general, the red muscle possesses the highest fatty acid oxidation capacity, however, by taking into consideration the fact that white muscle occupies approximately 60% of the total body weight, this study demonstrates that the white muscle is an important tissue in the overall fatty acid catabolism.

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Citations in the corpus

Metabolism and Functions of Lipids and Fatty Acids in Teleost Fish (2003, background): “As noted above, a major role of lipids in fish is for the storage and provision of metabolic energy in the form of ATP provided through the β-oxidation of fatty acids (Sargent et al., 1989; Froyland et al., 2000).”
Growth, feed utilization and flesh quality of European sea bass (Dicentrarchus labrax) fed diets containing vegetable oils: A time-course study on the effect of a re-feeding period with a 100% fish oil diet (2005, background): “Mitochondrial beta-oxidation is of special importance in muscle (Froyland et al., 2000), thus the levels of C18 fatty acids were higher in liver than in muscle.”
Effects of dietary lipid level and vegetable oil on fatty acid metabolism in Atlantic salmon (Salmo salar L.) over the whole production cycle (2003, methodology): “Measurement of fatty acid oxidation by estimation of acid-soluble radioactivity after incubating intact cells with labelled fatty acids has been described previously ( Froyland et al. 1996, 2000; Madsen et al. 1998; Torstensen et al. 2000; Tocher et al. 2002).”
Effects of fatty acid composition and spawning season patterns on egg quality and larval survival in common snook (Centropomus undecimalis). (2009, background): “Apart of their role as being a major source of metabolic energy (Sargent et al.,1989; Froyland et al., 2000; Sargent et al., 2002; Tocher, 2003), Fatty acids (FA), and particularly Polyunsaturated fatty acids (PUFA), are functionally essential for normal growth, development and reproduction in fis”
Towards Fish Lipid Nutrigenomics: Current State and Prospects for Fin-Fish Aquaculture (2008, background): “However, although having a low β-oxidation capacity per gram of tissue, white muscle has been shown to be the major site for β-oxidation due to the overall size of the tissue (Froyland et al. 2000; Nanton et al. 2003; Stubhaug et al. 2005).”
Effect of partial substitution of dietary fish oil by vegetable oils on desaturation and β-oxidation of [1-14C]18:3n−3 (LNA) and [1-14C]20:5n−3 (EPA) in hepatocytes and enterocytes of European sea bass (Dicentrarchus labrax L.) (2005, methodology): “The assay of fatty acid oxidation in intact hepatocytes requires the determination of acidsoluble radioactivity as described in detail previously (Frøyland et al. 2000; Torstensen et al. 2000).”
Effects of diets containing linseed oil on fatty acid desaturation and oxidation in hepatocytes and intestinal enterocytes in Atlantic salmon (Salmo salar) (2002, methodology): “In Atlantic salmon, fatty acid oxidation is predominantly mitochondrial β-oxidation with peroxisomal β-oxidation accounting for less than 10% of total oxidation (Frøyland et al. 2000).”