Adipose tissue as an endocrine organ.

By S. Galic, J. Oakhill, G. Steinberg. Molecular and Cellular Endocrinology, 2010

4,906 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/99e0ff0e857528caec61bd9a7f87fbd2c29f97aa

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In Endocrine and Autonomic Systems

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Citations in the corpus

Towards Fish Lipid Nutrigenomics: Current State and Prospects for Fin-Fish Aquaculture (2008, background): “and cytokines, which act at various sites to regulate energy homeostasis (Ahima, 2006).”
In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high fat feeding (2012, neutral): “A substantial body of evidence indicates that adipose tissue dysfunction contributes importantly to the adverse outcomes associated with obesity (Galic et al., 2010) and that recruitment of beneficial cellular phenotypes might offer a means of thera- peutic intervention (Sethi and Vidal-Puig, 2007).”
The impact of maternal obesity on maternal and fetal health. (2008, background): “Indeed, most if not all circulating estradiol in postmenopausal women comes directly from adipose tissue.(9) Adipose tissue expresses 11 -hydroxysteroid dehydrogenase type 1 (11 -HSD1), which converts cortisone to cortisol, as well as 5 -reductase, which converts cortisol to 5 -tetrahydrocortisol.”
Adiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial Dysfunction (2017, background): “Adipose tissue, commonly called “fat”, is a type of loose connective tissue comprised of lipid-filled cells (adipocytes) surrounded by a matrix of collagen fibers, blood vessels, fibroblasts, and immune cells [8].”
Sex differences in human adipose tissues – the biology of pear shape (2012, background): “and their individual roles have been reviewed extensively ([141,142] among others).”
Obesity and Free Fatty Acids (FFA) (2008, background): “As mentioned earlier, adipose tissue produces and releases a large number of cytokines and chemokines (collectively called adipokines) [4], some of which are proinflammatory.”
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2 (2012, background): “IKKβ and JNK—Impaired glucose uptake and/or insulin resistance within adipose tissue can contribute to the development of type 2 diabetes [164], likely by altering its secretion of adipokines, such as adiponectin or retinol-binding protein 4 (reviewed in [165]).”
Forming functional fat: a growing understanding of adipocyte differentiation (2011, neutral): “jpg"/> Adipose tissue is a complex organ that regulates and coordinates energy homeostasi”
The role of FoxO in the regulation of metabolism (2008, background): “In addition, adipocytes secrete a number of hormones and cytokines, including leptin and adiponectin, which increase insulin sensitivity (Ahima and Flier, 2000).”
A comprehensive definition for metabolic syndrome (2009, background): “The mechanisms for this probably involve adipokines, which are made by adipose tissue, that modulate crosstalk between metabolism and vascular function (Kershaw and Flier, 2004).”
Cardiac remodeling in obesity. (2008, background): “Adipose tissue, once considered simply a lipid storage depot, is now known to produce and secrete an ever increasing range of factors, collectively termed “adipokines” (175).”
Obesity and female infertility: potential mediators of obesity's impact. (2017, background): “is an endocrine organ that produces many proinflammatory adipokines, including leptin, tumor necrosis factor a, and interleukin (IL) 6 (42).”
Mechanisms of leptin action and leptin resistance. (2008, background): “Indeed , the obesity and cellular leptin resistance of DIO animals are reversed by replacing the palatable calorie-dense chow used to promote obesity with standard chow (33).”