Cancer chemoprevention with dietary phytochemicals

By Y. Surh. Nature Reviews. Cancer, 2003

3,006 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/43742db87289b692aa6ec9d83ebee42a2fc22c74

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Citations in the corpus

Natural Phenolic Compounds From Medicinal Herbs and Dietary Plants: Potential Use for Cancer Prevention (2009, background): “There are now more than 10 million cases of cancer per year worldwide, including a group of more than 100 diseases such as cancer of the liver, lung, stomach, colon, breast, and so forth ( 2 , 3 ).”
Nrf2:INrf2(Keap1) Signaling in Oxidative Stress (2009, positive): “Inducers of Nrf2 function as blocking agents that prevent carcinogens from reaching target sites, inhibit parent molecules from undergoing metabolic activation, or subsequently prevent carcinogenic species from interacting with crucial cellular macromolecules, such as DNA, RNA, and proteins [72].”
Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms (2018, positive): “, phytoestrogens), can compete with endogenous estrogens in binding to the estrogen receptors, and thus blocking its mitogenic effects (72).”
Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. (2006, background): “Recent research is clarifying that many dietary cancer chemopreventive agents exert their effects by modulating one or more cell signaling pathways in a manner that interrupts the carcinogenic process (2).”
Free radicals and antioxidants in human health: current status and future prospects. (2004, background): “(Croce, 2001).27 Surh (2003)28 recently reviewed mechanisms behind anticancer effects of dietary phytochemicals.”
Molecular targets of dietary agents for prevention and therapy of cancer. (2006, neutral): “[73] Surh YJ.”
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells (2009, neutral): “It has been well known that dietary chemopreventive agents inhibit cancer cell growth in vitro and in vivo through the regulation of cell signaling transduction (21, 22).”
How Do Nutritional Antioxidants Really Work: Nucleophilic Tone and Para-Hormesis Versus Free Radical Scavenging in vivo (2013, neutral): “As an example, the concept of cancer prevention, and possibly reversion, by phytochemicals present in fruit and vegetables is usually discussed with regard to the alleged antioxidant effect brought by a plethora of antioxidant compounds present in vegetal foods [6].”
Inflammation: gearing the journey to cancer. (2008, background): “Numerous synthetic and natural compounds with antiinflammatory properties have been identified as attractive chemopreventive arsenal [119,255].”
Cancer preventive properties of ginger: a brief review. (2007, background): “Some phytochemicals derived in spices and herbs as well as other plants possess substantial cancer preventive properties (Lai and Roy, 2004; Surh, 2002, 2003).”
Drug discovery from medicinal plants. (2005, background): “As such, herbal medicines, botanicals, dietary supplements, and edible plants have all been suggested as potentially important in cancer chemoprevention due to their long history of human consumption (Park and Pezzuto, 2002; Reddy et al., 2003; Surh, 2003; Kinghorn et al., 2004).”
Cancer Chemoprevention Through Dietary Antioxidants: Progress and Promise (2008, neutral): “Various epidemiological evidences suggest that intake of fruits, vegetables, and whole grains may reduce cancer risk in some individuals, and this has been attributed to these foods being rich sources of numerous bioactive compounds (216, 275).”
The flavonoid quercetin in disease prevention and therapy: facts and fancies. (2012, background): “The vegetable kingdom is an almost inexhaustible source of phytochemicals with potential chemotherapeutic and chemopreventive activities [2].”
NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK. (2008, background): “Since a variety of anti-inflammatory or anti-carcinogenetic phytochemicals suppresses NF-κB signaling and activates Nrf2ARE pathway as well [25–27], one may ask if the suppression of NF-κB signaling and the activation of Nrf2-ARE pathway are totally independent or may crosstalk with each other in so”