The gut microbiota, bacterial metabolites and colorectal cancer

By P. Louis, G. Hold, H. Flint. Nature Reviews Microbiology, 2014

2,513 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/11161856aef9ecf04b0659a9faca2e484596e321

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Citations in the corpus

Microbiota metabolite short chain fatty acids, GCPR, and inflammatory bowel diseases (2016, background): “Butyrate is produced from Acetyl-CoA by several Firmicutes.”
Probiotics, gut microbiota, and their influence on host health and disease (2017, background): “In this regard, butyrate producers play a key role in the maintenance of the epithelial barrier, since butyrate is one of the main energy sources of enterocytes [64].”
SCFA: mechanisms and functional importance in the gut (2020, background): “Propionate is a precursor for the synthesis of glucose in the liver((20,25,85)).”
Probiotics in Fish Nutrition—Long-Standing Household Remedy or Native Nutraceuticals? (2021, background): “to G-coupled protein receptors, which are expressed in neutrophils, macrophages, and monocytes [136,137].”
Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health (2016, background): “Remarkably, the production of butyrate and propionate by the same bacterium is not common and only a few anaerobes, such as Roseburia inulinivorans and Coprococcus catus, are able to produce both (Louis et al., 2014).”
Fusobacterium nucleatum and T-cells in Colorectal Carcinoma (2015, neutral): “04 Q2 (11-23) 137 (25) 118 (25) 6 (18) 13 (35)”
Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects. (2016, background): “…microbes can directly be transforming agents (Sears and Garrett, 2014) by providing a toxic metabolite, an oncogenic product or inducing an inflammatory milieu which will culminate in genomic instability and/or DNA damage responses and/or immune escape (Gur et al., 2015; Louis et al., 2014).”
Formation of propionate and butyrate by the human colonic microbiota. (2017, background): “New mechanisms by which SCFA regulate immune cell development and suppress inflammation have been uncovered recently (Louis et al., 2014; Richards et al., 2016).”
Gut Microbiota-Derived Short-Chain Fatty Acids, T Cells, and Inflammation (2014, background): “tyryl-CoA:acetate CoA-transferase, which is active in some bacteria including Roseburia, Eubacterium and Anaerostipes species and Faecalibacterium prausnitzii (27,32).”
The Effect of Probiotics on the Production of Short-Chain Fatty Acids by Human Intestinal Microbiome (2020, background): “Most often it is fermentation of indigestible carbohydrates, while about 1/3 of acetic acid is formed as a result of synthesis from hydrogen and carbon dioxide or formic acid by acetogenic bacteria through the Wood–Ljungdahl pathway [31,35].”