Formation of propionate and butyrate by the human colonic microbiota.

By P. Louis, H. Flint. Environmental Microbiology, 2017

2,495 citations recorded by the source corpus.

Subfields: Food Science, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/b7e92af2f4696bc7a2766f41b135e7e34c0f597d

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Citations in the corpus

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling (2020, result): “The results were correlated to the NGSbased abundance of the dominant butyrate-producing genera Subdoligranulum, Faecalibacterium, Anaerostipes, Butyrivibrio, and Roseburia/Eubacterium rectale [26, 27].”
Impact of Omega-3 Fatty Acids on the Gut Microbiota (2017, background): “A statistically increased abundance of Bifidobacterium and Oscillospira genera, associated with a reduction of Coprococcus and Faecalibacterium, were found after both omega-3 PUFA supplementations in comparison with before the study and after washout.”
Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota (2023, background): “Butyryl-CoA is then transformed in butyrate via butyryl-CoA:acetate CoA-transferase or via phosphotransbutyrylase and butyrate kinase [89].”
Dynamics of Human Gut Microbiota and Short-Chain Fatty Acids in Response to Dietary Interventions with Three Fermentable Fibers (2018, background): “However, most resistant starch degraders are not among known butyrate producers (19, 21).”
The Controversial Role of Human Gut Lachnospiraceae (2020, background): “rectale share the butyryl-CoA:acetate CoA-transferase route and the same gene organization to form butyryl-CoA from two molecules of acetyl-CoA [40].”
Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases (2019, background): “Bacteroidetes (gram-negative) and Firmicutes (gram-positive) are the most abundant phyla in the intestine, with members of the Bacteroidetesmainly producing acetate and propionate, while Firmicutes mostly produce butyrate in the human gut (33, 34).”
Butyrate: A Double-Edged Sword for Health? (2018, background): “In the first pathway, butyryl-CoA is phosphorylated to form butyrylphosphate and transformed to butyrate via butyrate kinase (22).”
Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism (2020, background): “Among them, acetate (C2), propionate (C3), and butyrate (C4) are the most abundant (≥95%) [1], and the C2, C3, and C4 are in an approximate molar ratio of 60:20:20, respectively [2,3].”
Short chain fatty acids and its producing organisms: An overlooked therapy for IBD? (2021, methodology): “To produce propionate, two pathways are possible, namely, the succinate pathway used by Bacteroidetes and Negativicutes (Firmicutes phylum), and the propanediol pathway used by Lachnospiraceae [11].”
Gut microbiota functions: metabolism of nutrients and other food components (2017, background): “It is important to note that propionate and butyrate are also formed from peptide and amino-acid fermentation by certain Bacteroidetes and Firmicutes species [21].”
The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication (2020, background): “Although anaerobic fermentation of fibers is the largest source of SCFAs, acetate, propionate, and butyrate can also be produced from amino acid metabolism (68).”