Ralph DeFronzo

Endocrinology, Diabetes and Metabolism · 2000–2023

A researcher in the Science corpus: 27 papers; trusts 37 researchers and is trusted by 13 researchers here, as inferred from the citation graph.

Subfields

• Endocrinology, Diabetes and Metabolism — 237 citations into it; #57 of 623 by trust here, #32 by citations
• Molecular Biology — 227 citations into it; #3,064 of 17,773 by trust here, #1,510 by citations
• Physiology — 163 citations into it; #1,690 of 2,276 by trust here, #206 by citations
• Epidemiology — 135 citations into it; #651 of 2,148 by trust here, #348 by citations
• Surgery — 97 citations into it; #233 of 1,106 by trust here, #412 by citations
• Genetics — 84 citations into it
• Cardiology and Cardiovascular Medicine — 43 citations into it
• Endocrine and Autonomic Systems — 32 citations into it

Whom Ralph DeFronzo trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. K. Petersen
2. D. J. Drucker
3. D. Kelley
4. S. Kahn
5. Lawrence J. Mandarino
6. Jens J. Holst
7. D. Nathan
8. Rury R. Holman
9. H. Bays
10. P. Puigserver

Who trusts Ralph DeFronzo overall

1. K. Bornfeldt
2. I. Tabas
3. C. Janani
4. Muhammad Abdul-Ghani
5. D. J. Drucker
6. M. Qatanani
7. M. Nauck
8. K. Cusi
9. F. Alsaraj
10. V. Basevi

Papers from Ralph DeFronzo's perspective

Ordered by how strongly the researchers Ralph DeFronzo trusts endorse each paper. Same corpus, a different order for every researcher.

1. The hormone resistin links obesity to diabetes (Nature)
2. Faculty Opinions recommendation of PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.
3. Prevention of fat-induced insulin resistance by salicylate. (Journal of Clinical Investigation)
4. Numerical Recipes in C: The Art of Scientific Computing
5. Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ (Science)
6. Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α
7. Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. (Journal of Clinical Investigation)
8. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 (Proceedings of the National Academy of Sciences of the United States of America)
9. Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance (Science)
10. Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. (Diabetes)

Their papers

• Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 (2003) — 2,100 citations
• The genetic architecture of type 2 diabetes (2016) — 1,066 citations
• Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. (2004) — 683 citations
• Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. (2004) — 692 citations
• Pioglitazone for diabetes prevention in impaired glucose tolerance. (2011) — 716 citations
• Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. (2000) — 1,165 citations
• From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus (2009) — 2,673 citations
• Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. (2005) — 1,627 citations
• Impaired Fasting Glucose and Impaired Glucose Tolerance (2007) — 939 citations
• Contributions of β-Cell Dysfunction and Insulin Resistance to the Pathogenesis of Impaired Glucose Tolerance and Impaired Fasting Glucose A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances. (2006) — 630 citations
• Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes (2009) — 1,906 citations
• Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009 (2010) — 888 citations
• Pathogenesis of type 2 diabetes mellitus. (2004) — 843 citations
• Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance (2009) — 633 citations
• Metformin-associated lactic acidosis: Current perspectives on causes and risk. (2016) — 610 citations
• Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial. (2015) — 1,033 citations
• Type 2 diabetes mellitus (2015) — 2,875 citations
• Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. (2023) — 670 citations
• Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico (2013) — 472 citations
• Non-Alcoholic Fatty Liver Disease (NAFLD) and Its Connection with Insulin Resistance, Dyslipidemia, Atherosclerosis and Coronary Heart Disease (2013) — 772 citations