Antigen presentation and T cell stimulation by dendritic cells.

By P. Guermonprez, J. Valladeau, L. Zitvogel, C. Théry, S. Amigorena. Annual Review of Immunology, 2002

2,074 citations recorded by the source corpus.

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Citations in the corpus

ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. (2005, background): “Three major findings on exosomes produced by mature DCs are reported here: (1) these exosomes induce effector T-cell responses, since they induce rapid rejection of antigen-bearing grafts, (2) they can transfer not only MHC-peptide complexes, but also T-cell– stimulating ability to poorly efficient ”
Inflammasomes and their roles in health and disease. (2012, background): “…to these first-line responses, dendritic cells and other professional antigen-presenting cells capture and display immunogenic fragments of the hostile factor on their surface as a way of communicating the identity of the harmful agent to the adaptive immune system (Guermonprez et al. 2002).”
Immunosuppressive strategies that are mediated by tumor cells. (2007, background): “It has been shown that if APCs fail to provide an appropriate co-stimulatory signal for T cells, tolerance or anergy can develop (27, 140).”
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. (2006, background): “Phagocytosed antigens are presented to CD8+ T lymphocytes through a process called ‘‘crosspresentation’’ (Guermonprez et al., 2002; Heath et al., 2004).”
Size-Dependent Immunogenicity: Therapeutic and Protective Properties of Nano-Vaccines against Tumors1 (2004, background): “In this context, it is important to note that DC are particularly efficient at diversion of endosomal/phagosomal (23) Ags for MHC class I presentation (24, 25), and by patocytosis, an uptake mechanism for some hydrophobic nano-particles with the potential to deliver Ags into the cytosol (17, 26).”
Regulation of the immune response by the aryl hydrocarbon receptor (2018, background): “Dendritic cells (DCs) have a central role in the control of T cell responses and the regulation of immune tolerance (Guermonprez et al., 2002).”
ER–phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells (2003, background): “jpg" NDATA ITEM> ]> Induction of cytotoxic T-cell immunity requires the phagocytosis of pathogens, virus-infected or dead tumour cells by dendritic cell”