The neurotrophin hypothesis for synaptic plasticity.

By A. F. Schinder, Mu-Ming Poo. Trends in Neurosciences, 2000

751 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/e80e0e794f94586ce6082bf3abb5e8cad4607a16

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In Cellular and Molecular Neuroscience

In Developmental Neuroscience

Citations in the corpus

Brain-Derived Neurotrophic Factor Induces Long-Term Potentiation in Intact Adult Hippocampus: Requirement for ERK Activation Coupled to CREB and Upregulation of Arc Synthesis (2002, background): “In a recent review, Schinder and Poo (2000) asked whether neurotrophins play an “instructive” role in LTP by inducing synaptic potentiation or a “permissive” role by maintaining housekeeping functions that are necessary for the induction and maintenance of LTP.”
Neurotrophin secretion: current facts and future prospects. (2003, background): “Today the role of BDNF in long-term synaptic plasticity in the hippocampus and neocortex is well established (reviewed, e.g. inLessmann, 1998; Schuman, 1999; Schinder and Poo, 2000; Poo, 2001), and it will only be briefly summarized here.”
Breathing: rhythmicity, plasticity, chemosensitivity. (2003, background): “…postsynaptic membrane (Grosshans et al. 2002, Malinow & Malenka 2002); (ii) phosphorylating glutamate receptors (Czapla et al. 1999); (iii) increasing glutamate release (Schinder & Poo 2000); and/or (v) decreasing GABA-mediated neurotransmission (Henneberger et al. 2002) onto phrenic motoneurons.”
Effects of Physical Activity on Children’s Executive Function: Contributions of Experimental Research on Aerobic Exercise (2010, background): “For another example, a task-switching paradigm assesses the shifting component (Tomporowski, Davis, Lambourne, Gregoski, & Tkacz, 2008).”
Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. (2004, background): “…is the most widely distributed neurotrophin in the adult mammalian brain, and there is growing evidence to suggest its involvement in activity-dependent synaptic plasticity (Schuman, 1999; Schinder and Poo, 2000; Binder et al., 2001; Ying et al., 2002; Messaoudi et al., 2002; Gooney et al., 2002).”
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. (2002, background): “The extensive literature on the role of NTs in synaptic plasticity, including neurotransmitter release and intracellular signaling cascades , has been reviewed in recent articles (Segal and Greenberg 1996; Schinder and Poo 2000; Thoenen 2000; Poo 2001; Tyler et al. 2002).”
BDNF is essential to promote persistence of long-term memory storage (2008, background): “BDNF regulates neuronal structure and function (8, 9).”
Neurotrophins and their receptors: A convergence point for many signalling pathways (2003, background): “Despite considerable evidence for the effects of neurotrophins on synaptic strengt”
A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. (2002, background): “Increasing evidence indicates that BDNF has the capacity to convert changes in electrical activity to long-lasting changes in synaptic strength and function (Poo, 2001; Schinder and Poo, 2000).”
BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. (2005, background): “While neurotrophins traditionally were thought to operate on a time scale of days and weeks, rapid effects have now been demonstrated on a host of cellular functions including ion channel activity, neurotransmitter release, and axon pathfinding (Song and Poo, 1999; Schinder and Poo, 2000; Kovalchuk ”
Neurotrophins as synaptic modulators (2001, background): “Aspects of this subject have been covered by several recent review”
Brain-derived neurotrophic factor. (2004, background): “via phosphorylation of neurotransmitter receptors) is intensely debated (Schinder and Poo, 2000) (Fig.”