BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis.

By C. Bramham, ElHoucine Messaoudi. Progress in neurobiology, 2005

1,251 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/e1c037f48f1e738ee13145ca0f2568bd8cfde571

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Malenka
2. A. Citri
3. Peter W. Kalivas
4. C. O'Brien
5. B. Casey
6. E. Bruel-Jungerman
7. J. Sweatt
8. Felipe Fregni

In Developmental Neuroscience

1. R. Malenka
2. A. Citri
3. F. Lubin
4. T. Roth
5. E. Bruel-Jungerman
6. J. Sweatt
7. B. Casey
8. S. Laroche

Citations in the corpus

• Drug Addiction as a Pathology of Staged Neuroplasticity (2008, background): “Interestingly, stimulating BDNF receptors promotes actin cycling and modulates spine density (Bramham and Messaoudi, 2005), indicating that the afore-mentioned progressive elevation of BDNF during withdrawal may contribute directly to the enduring adaptations in excitatory transmission.”
• Dendritic mRNA: transport, translation and function (2007, background): “Several lines of evidence suggest that BDNF stimulates LTP consolidatio”
• Brain-derived neurotrophic factor and its clinical implications (2015, background): “This paracrine (retrograde messenger) role of BDNF was later confirmed, and it was shown that application of BDNF to hippocampal sections restored spine actin polymerization and LTP (longterm potentiation) stability in rats [70].”
• Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain (2019, background): “Due to its critical role in LTP, BDNF has been postulated to be an essential part of the cellular mechanism supporting memory formation and maintenance by promoting synaptic consolidation (Bramham and Messaoudi, 2005).”
• EPIGENETIC REGULATION OF BDNF GENE TRANSCRIPTION IN THE CONSOLIDATION OF FEAR MEMORY (2008, background): “Brain-derived neurotrophic factor (BDNF) has been shown to contribute to neuronal activity-dependent processes such as long-term potentiation (Bramham and Messaoudi, 2005; Soulé et al., 2006), a leading candidate cellular mechanism for associative memory formation (Bliss and Collingridge, 1993;…”
• The Adolescent Brain and the Emergence and Peak of Psychopathology (2015, background): “BDNF is thought to play an important role in learning and plasticity (Bramham & Messaoudi, 2005; Mahan & Ressler, 2012), which is essential for learning when cues no longer signal threat but safety.”
• Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms (2008, result): “In addition, there is evidence suggesting a role for secreted BDNF in driving the opposite form of synaptic scaling; the decrease in synaptic strengths caused by extended periods of increased network acitivity (Rutherford et al, 1998; Turrigiano, 2006).”
• A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. (2008, background): “In addition, BDNF is particularly associated with the late phases of long-term potentiation (LTP), the property of neurons in increasing synaptic strength (Gartner and Staiger, 2002), which evolves protein synthesis and de-novo gene expression (Bramham and Messaoudi, 2005).”
• BDNF-induced local protein synthesis and synaptic plasticity. (2014, neutral): “The neurotrophin brain-derived neurotrophic factor (BDNF) has been shown to play a key role asmediator of activity-induced LTP in the hippocampus as well as in other brain regions (Bramham and Messaoudi, 2005; Cowansage et al., 2010; Lu et al., 2008; Minichiello, 2009; Park and Poo, 2013; Santos et ”
• Long-Term Potentiation Enhances Neurogenesis in the Adult Dentate Gyrus (2006, background): “For example, LTP is associated with release of many proteins including neurotrophic factors such as BDNF, and BDNF gene expression is enhanced for at least 24 h after LTP in the DG (Bramham and Messaoudi, 2005).”