Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Development

By I. Okamoto, A. Otte, C. D. Allis, D. Reinberg, Edith Heard. Science, 2004

828 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e6f53a64e6ec40c012d86b6e42a117a359fc5b96

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Citations in the corpus

Capture of authentic embryonic stem cells from rat blastocysts. (2008, positive): “A hallmark of female ES cells and early epiblast is that both X chromosomes are active (Mak et al., 2004; Okamoto et al., 2004; Rastan and Robertson, 1985).”
Covalent modifications of histones during development and disease pathogenesis (2007, background): “Recent studies have highlighted the roles of histone modifications and an untranslated RNA, namely Xist, in both imprinted and random X chromosome inactivatio”
The diverse functions of histone lysine methylation (2005, background): “Early in mouse development, imprinted X inactivation, in which the paternal chromosome is inactivated, occurs in all cells of the embryo 68,69 .”
Stability and flexibility of epigenetic gene regulation in mammalian development (2007, background): “Random X-chromosome inactivation is initiated in the epiblast after reprogramming of imprinted inactivatio”
Child health, developmental plasticity, and epigenetic programming. (2011, background): “The initiation of X-inactivation is thought to be tightly correlated with early differentiation events during development (311); Xp undergoes imprinted inactivation from the cleavage stages onward, well before cellular differentiation.”
Meiotic sex chromosome inactivation (2007, neutral): “One study (Huynh and Lee, 2003) found evidence for paternal X chromosome inactivation from the two-cell stage, whereas the other (Okamoto et al., 2004) found that inactivation begins at the four-to-eight-cell stage, when Xist expression is initiated.”
Long Noncoding RNAs: Past, Present, and Future (2013, background): “…types of XCI: imprinted XCI in the fertilized embryo and extraembryonic tissues, where the paternal X is always inactivated (Takagi and Sasaki 1975; Okamoto et al. 2004), and random XCI, occurring in the inner cell mass (which becomes the embryo proper), where epigenetic marks have been erased…”
The Polycomb Group Protein Suz12 Is Required for Embryonic Stem Cell Differentiation (2007, background): “(31); and rabbit anti-Nanog and rabbit anti-Oct4 from Abcam.”
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo (2009, background): “The Polycomb group protein Eed marks the inactive paternal X chromosome in early embryos (Mak et al., 2004; Okamoto et al., 2004).”
Epigenetic reprogramming in mammals. (2005, background): “The imprinted inactive X chromosome becomes reprogrammed and the X chromosomes are randomly inactivated (67).”
Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos (2016, neutral): “The paternal X chromosome is thereafter kept inactivated in the TE and PE lineages, while reactivation and a round of random XCI takes place in the pre- and peri-implantation stage epiblast (Heard et al., 2004; Monk and Harper, 1979; Okamoto et al., 2004; Takagi and Sasaki, 1975).”
Nanog Is the Gateway to the Pluripotent Ground State (2009, neutral): “In female mouse embryos the paternal X chromosome is silenced during early cleavage (Okamoto et al., 2004).”
A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. (2006, result): “This is consistent with our previous study in embryos (Okamoto et al. 2004).”
Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. (2004, background): “We discuss these results in the context of under- results in imprinted inactivation of the paternal X chrostanding the mechanism of action and evolution of PRC1 mosome (Xp) in all cells of late morula and early blastoPcG proteins. cyst stage embryos (Okamoto et al., 2004; Mak et al., 2004).”