Epigenetic reprogramming in mammals.

By H. Morgan, Fátima Santos, Kelly Green, W. Dean, Wolf Reik. Human Molecular Genetics, 2005

1,387 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/aa6f13667d3674b339f55111925b469e11964ea3

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Citations in the corpus

Dynamic CpG island methylation landscape in oocytes and preimplantation embryos (2011, background): “864" language="eng" relation="no"> Elucidating how and to what extent CpG islands (CGIs) are methylated in germ cells is essential to understand genomic imprinting and epigenetic reprogrammin”
Epigenetic Gene Regulation in the Bacterial World (2006, background): “A major area of research in eukaryotic epigenetic regulation is directed at understanding the mechanisms by which DNA methylation patterns are erased following cleavage of the fertilized egg and then established via de novo methylation (74, 81, 141, 180).”
Inherited epigenetic variation — revisiting soft inheritance (2006, background): “The first is the widespread evidence for erasure of epigenetic marks in a developmental contex”
DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45 (2008, neutral): “In regard to thefirst mechanism, vertebrates contain orthologs of the bacterial AlkB demethylases (dioxygenases) which operate through direct methyl removal in prokaryotes ( Morgan et al., 2005; Sedgwick, 2004).”
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. (2009, neutral): “This might be inherent to mammalian development (26,27) and this hypothesis is also supported by detailed animal studies (28,29).”
Active DNA Demethylation Mediated by DNA Glycosylases (2009, neutral): “Even during this so-called global demethylation, some regions of the genome, including certain heterochromatic sequences, retrotransposons, and paternally methylated imprinted genes, are not demethylated (73).”
CpG islands and the regulation of transcription. (2011, background): “A prediction of this hypothesis is that all CGI promoters should be active during the waves of de novo methylation that occur at the blastocyst stage and in developing germ cells of the embryo (Morgan et al. 2005).”
Epigenetic inheritance during the cell cycle (2009, background): “and during PGC development suggests, however, that DNA methylation can be removed by active mechanism”
Protamines and male infertility. (2006, background): “…factors and epigenetic changes during spermatogenesis have also been elegantly reviewed by different groups (Sassone-Corsi, 2002; Lewis et al., 2003b; Govin et al., 2004; Caron et al., 2005; Horsthemke and Ludwig, 2005; Kimmins and Sassone-Corsi, 2005; Morgan et al., 2005; Rousseaux et al., 2005).”
Stability and flexibility of epigenetic gene regulation in mammalian development (2007, background): “Therefore, our lack of understanding of how epigenetic marks are reprogrammed is a key obstacle to clonin”
DNA hypomethylation and human diseases. (2007, background): “The demethylase activity is present in the oocyte, but the molecular mechanism underlying the process is not yet established [118].”