Transcriptional silencing and promoter methylation triggered by double‐stranded RNA

By M. Mette, W. Aufsatz, J. Winden, M. Matzke, A. Matzke. EMBO Journal, 2000

942 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e5488d4bb236ac96d4b7637e8f65e54167857b4d

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In Plant Science

Citations in the corpus

RNA silencing in plants (2004, background): “The first evidence for this type of silencing was the discovery in plants that transgene and viral RNAs guide DNA methylatio”
New plant breeding techniques. State-of-the-art and prospects for commercial development (2011, background): “Inverted Repeat (IR) constructs seem to be the most effective (Mette et al., 2000; Muskens et al., 2000).”
Genetic and Functional Diversification of Small RNA Pathways in Plants (2004, background): “Exogenous siRNAs can arise from both sense and hairpin transcript-forming transgenes and by viruses (Hamilton and Baulcombe 1999; Mette et al. 2000).”
Improvement of salinity stress tolerance in rice: Challenges and opportunities (2016, background): “Transcriptional gene silencing is an irreversible process that occurs when dsRNA molecules target promoter regions resulting in methylation and termination of transcription [150,151].”
The profile of repeat‐associated histone lysine methylation states in the mouse epigenome (2005, background): “These include RNAi-triggered silencing (Ratcliff et al, 1997; Mette et al, 2000; Vastenhouw and Plasterk, 2004), DNA methylation (Jaenisch and Bird, 2003; Bourc’his and Bestor, 2004) and histone modifications (Jenuwein and Allis, 2001).”
Perspective: machines for RNAi. (2005, background): “DsRNA targeting promoter sequences also trigger transcriptional silencing in plants (Mette et al. 2000).”
Evolutionary genetics of genome merger and doubling in plants. (2008, background): “The time-scales are not absolute, and the terms neopolyploidy and paleopolyploidy are used variously by different authors linked, such as methylation and histone modification, each of which has the ability to silence genes (68, 83, 87).”
Non‐coding RNAs: the architects of eukaryotic complexity (2001, background): “…variegation, imprinting, DNA methylation, X-chromosome dosage compensation and transvection, all of which share features in common (Judd, 1995; Fire, 1999; Jones et al., 2000; Kelley and Kuroda, 2000; Mette et al., 2000; Morel et al., 2000; Sleutels et al., 2000; Wassenegger, 2000; Sharp, 2001).”
Small silencing RNAs: an expanding universe (2009, positive): “casiRNAs promote heterochromatin formation by directing DNA methylation and histone modification at the loci from which they originat”
Non‐coding RNAs: regulators of disease (2010, background): “Indeed it appears that RNA signalling is central to all complex genetic phenomena in the eukaryotes, including transcriptional and post-transcriptional gene silencing [13–22], hybrid dysgenesis [15,23], Xchromosome dosage compensation and allelic exclusion [24,25], germ cell reprogramming [26] and p”
The role of RNA interference in heterochromatic silencing (2004, background): “In contrast, silencing of a bacterial transgene can be achieved using inverted repeats of the nopaline synthase promoter (NOSpro) alon”