Control of Stem Cell Self-Renewal in Drosophila Spermatogenesis by JAK-STAT Signaling

By N. Tulina, E. Matunis. Science, 2001

677 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c740c3a2d046ed7e40dca6c33122277cf036818e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. D. Scadden
2. S. Morrison
3. Linheng Li
4. A. Spradling
5. M. Fuller
6. Juergen A. Knoblich

In Immunology

1. S. Morrison
2. M. Clarke
3. D. Scadden
4. M. Fuller
5. A. Spradling

In Molecular Biology

1. S. Morrison
2. Linheng Li
3. D. Scadden
4. M. Clarke
5. A. Spradling
6. M. Fuller
7. T. Xie
8. Ben Scheres

Citations in the corpus

• BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. (2003, neutral): “These two pathways also mediate of the STAT pathway in male germ cells (Kiger et al.,ventralization of the Xenopus embryo (Nishinakamura 2001; Tulina and Matunis, 2001).”
• Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. (2008, background): “For example, showing that GSCs are maintained at the gonad tips by local signals suggested the existence of a niche (Kiger et al., 2001; Tulina and Matunis, 2001; Xie and Spradling, 1998); but demonstrating that new stem cells can be introduced and maintained there provided the clearest evidence (Br”
• The stem-cell niche as an entity of action (2006, background): “Within the Drosophila testis, Unpaired (UPD) is secreted by niche (hub) cells and induces stem-cell self-renewal via Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signallin”
• Stem cell niche: structure and function. (2005, background): “They either are progressively restricted in development, giving rise to multiple lineages (including tissue-specific cells), or are unipotent, giving rise to single lineage cells destined for certain tissues (Fuchs et al. 2004, Rossant 2004, Weissman 2000).”
• Stem cells and cancer: two faces of eve. (2006, background): “…niche, whereas the other daughter is displaced away from the Cell 124, M niche and activates expression of genes that launch this cell along the differentiation pathway (Chen and McKearin, 2003; Kiger et al., 2000, 2001; Tulina and Matunis, 2001; Xie and Spradling, 2000; Yamashita et al., 2003).”
• Signalling: STATs: transcriptional control and biological impact (2002, neutral): “Subsequently, the list of tissues (structures) known to be affected extended to — but is not limited to — wing veins, trachea, MONOCYTES , eye disc and eye development, as well as sex determination and germ cell”
• SCARECROW is involved in positioning the stem cell niche in the Arabidopsis root meristem. (2003, background): “Cap cells (Xie and Spradling 1998, 2000) and somatic hub cells (Kiger et al. 2001; Tulina and Matunis 2001) in Drosophila, distal tip cells in Caenorhabditis elegans (Kimble and White 1981), and cells expressing the homeodomain transcription factor WUSCHEL in the Arabidopsis shoot apical meristem (M”